Two-dimensional (2D) hexagonal microsheets of 8-hydroxyquinoline zinc (Znq2) were synthesized readily via a mixed solvent induced self-assembly method. The 2D optical waveguiding properties of the microsheets have been clearly revealed by both fluorescence microscopy and confocal microscopy. In addition, the reversible vapochromic properties of the microsheets have also been demonstrated when t...

EDITSHAL and usually, as in the present case, constructional apraxia will be detected with or without ideational apraxia, alexia, or sensory agnosia. Interpretation of Gerstmann's syndrome as an easily demonstrated and memorable pointer to diffuse cerebral damage accords well with this case, where there is no reason to suspect a highly focal lesion. Gerstmann's syndrome does not seem to have be...

Mixed ligand transition metal complexes having general formula ML 2 .HL', where M = Cu(II) or Pd(II); L = deprotonated 1-nitroso-2-naphthol or 8-hydroxyquinoline; HL' = picolinic acid or quinaldinic acid have been synthesised and characterised on the basis of Infrared, electronic absorption spectral data, magnetic and conductance measurements. The above study reveals the octahedral geometry of ...

It was shown that 5-chloro-8-hydroxyquinoline, an antituberculosis agent, gels aqueous alcohol solutions efficiently. Thermal stability and gel-to-sol transition temperature of 1% gel in CD₃OD/D₂O (2:1) was studied by ¹H-NMR. Fibrous structures of four xerogels have been characterized by scanning electron microscope.

Nitrite oxidase and nitrate reductase in Nitrobacter agilis were shown to be separate enzymes. The best separation of the two systems was achieved by ammonium sulphate fractionation. The effects of various compounds, including antimycin A, 2-n-heptyl-4-hydroxyquinoline N-oxide and chlorate, also clearly distinguish between the two enzyme reactions. The relationship between the two opposing reac...

A new series of potent 8-hydroxyquinolines was designed based on the newly resolved X-ray crystal structure of EGLN-1. Both alkyl and aryl 8-hydroxyquinoline-7-carboxyamides were good HIF-1alpha prolyl hydroxylase (EGLN) inhibitors. In subsequent VEGF induction assays, these exhibited potent VEGF activity. In addition, this class of compounds did show the ability to stabilize HIF-1alpha.