Background: Hyperthyroid has various effects on the cardiovascular system. Cardiac arrhythmias ranging from sinus tachycardia to atrial fibrillation and low/high cardiac output state congestive heart failure are observed in patients with hyperthyroidism. If hyperthyroidism is recognized treated early, dysfunction could be corrected. This case presentation will discuss importance of thyroid func...

Thyroid gland dysfunction is associated with disorders of female reproductive functions. The aim of this study was to examine the effects of hyperthyroidism on ovulation rate and peripheral sex steroid levels in prepubertal and adult rats. Two groups of female rats aging 30 days (prepubertal rats) and 60 days (adult rats) were made hyperthyroid by oral administration of levothyroxine daily...

We report herein a case of hyperthyroid Graves' disease developed from asymptomatic autoimmune thyroiditis (AAT). A 25-year-old single female with AAT was followed up for over 3 years. Thereafter her condition progressed to hyperthyroidism with both positive TSH receptor antibodies (TRAb) and an increase in antithyroidal antibodies. It is possible that there was continuous destruction of thyroi...

The “citric acid cycle” is now regarded as the final common pathway of metabolism serving as the primary route for the oxidation of metabolites. Likewise, the thyroid hormone is considered a major regulatory substance for biological oxidations. It, therefore, seemed logical to study possible quantitative alterations in the cycle acids in experimental hypoand hyperthyroid states. The concentrati...

The effects of altered thyroid hormones level (through induction of Hypothyroidism or Hyperthyroidism) on oxidative stress and antioxidant biomarkers as well as on gene expression of neuronal nitric oxide synthase and superoxide dismutase of adult male rat brain were studied. Hypothyroidism was induced by daily intraperitoneal (i.p.) injection of propylthiouracil (PTU, 10 mg/kg body weight) for...

OBJECTIVE Patients with Graves' disease were studied one year after radioiodine-131 therapy to assess the relationship between the effectiveness of the therapy and the radioiodine doses used. METHODS Patients were classified into three groups according to thyroid function as hyperthyroidism, euthyroidism and hypothyroidism at one year after I-131 therapy. In these groups we compared the mean ...

Upper gastrointestinal function in response to a mixed nutrient meal was evaluated in hyperthyroid patients, both before and after therapy, and in healthy controls. Gastric secretion, gastric emptying, and pancreatic secretion were all normal and normally integrated postprandially in the hyperthyroid patients. Bile acid output was reduced (P less than 0.05) in this group of patients relative to...

This paper presents a collection of 28 pristine symptoms which are used for the identification of Hyperthyroid disease which are heartwarming to humankind. Ghastly, Hyperthyroid affect people without being noticed until the end. In this Health Diagnose Expert Advisory System (HDEAS) we proposed a method for diagnosing the Hyperthyroid disease by enabling a list of symptoms that the person is li...

Objective: To evaluate potential role of serum leptin level in hyperthyroid female patients and find out its relationship with BMI. Setting: Atomic Energy Medical Centre and Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi. Methods: Serum leptin, FT3, FT4, TSH, serum triglyceride, total cholesterol, HDL-C, LDL-C were determined in 30 newly diagnosed untreated hypert...