The pattern of hair growth, morphology of the hair shafts, and the hair root state are described in four girls and two boys with prepubertal hypertrichosis. The exact nosology of this form of excessive hair growth is discussed in relation to hirsuties and the possibility of it representing an 'atavistic' trait.

BACKGROUND Stiff skin syndrome is a sclerodermalike disorder that presents in infancy or early childhood with rock-hard skin, limited joint mobility, and mild hypertrichosis in the absence of visceral or muscle involvement, immunologic abnormalities, or vascular hyperreactivity. OBSERVATIONS We describe 6 children who fit criteria for stiff skin syndrome. A review of the clinical range of thi...

BACKGROUND Radial graft is one of the optimal treatments for reconstruction after tongue cancer, but it is not free of side effects. Hypertrichosis over the graft, causing an intraoral paratrichosis, might downgrade the quality of life and even require further interventions. CLINICAL CASE The case is presented of a 58 year-old man, who developed hypertrichosis after surgery for tongue carcino...

Fibrous hamartoma of infancy (FHI) is a rare entity with a benign nature. The typical clinical features are a single, slowly growing, painless mass on the trunk that appears within the first 2 years of life. We report a 13-month-old boy who presented with a plaque on the lower back since 4 months of age. The plaque had gradually become larger and firm, and hyperhidrosis and hypertrichosis were ...

Hairs are complex structures, making a protective layer and serves different biological functions. TRPS1, a transcription factor is one of the candidate genes causing congenital hypertrichosis, an excessive hair growth at inappropriate body parts. SNPs of TRPS1 were retrieved from dbSNP which were screened by SIFT and PolyPhen servers based on their functional impacts. Out of the screened SNPs,...