The effect of various extracts (50% ethanolic) of Capparis decidua on lipid profile of streptozotocin diabetic rats was studied. The extract was administered to the diabetic models for 30days. The extract produced a significant (p<0.05) dose-dependent decrease in the levels of total cholesterol (TC), Triacylglycerol (TG), low-density lipoprotein-cholesterol (LDL cholesterol), with a significant...

BACKGROUND The effect of various extracts (50% ethanolic) of Capparis decidua on lipid profile of streptozotocin diabetic rats was studied. PROCEDURE The extract was administered to the diabetic models for 30days. FINDINGS The extract produced a significant (p<0.05) dose-dependent decrease in the levels of total cholesterol (TC), Triacylglycerol (TG), low-density lipoprotein-cholesterol (LD...

We studied the mechanisms of hypolipidemic effects of NIP-200 (3,5-dimethyl-4,6-diphenyltetrahydro-2H-1,3,5-thiadiazine- 2-thione), a potent hypolipidemic compound, in cholesterol biosynthesis in the liver, cholesterol absorption in small intestine, and cholesterol catabolism and excretion in rats. NIP-200 did not reduce cholesterol biosynthesis and had no effects on cholesterol absorption in t...

Effect of coconut protein in rats fed high fat cholesterol containing diet on the metabolism of lipids and lipid peroxides was studied. In addition, effect of coconut protein were compared with rats fed L-arginine. The results indicate that those fed coconut protein and those fed L-arginine showed significantly lower levels of total cholesterol, LDL+ VLDL cholesterol, Triglycerides and Phosphol...

Cardiovascular diseases continue to be a leading cause of morbidity and mortality in developed as well as developing countries. Hypercholesterolemia is one of the factors that have contributed in acceleration of Coronary Heart Diseases in India. It is associated with elevated lipid levels in the blood. Treatment of hypercholesterolemia is one of the major approaches towards decelerating the ath...

OBJECTIVE Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a predictor for incident atherosclerotic disease. We investigated the effect of 3 hypolipidemic drugs that exert their action through different mechanisms on plasma and lipoprotein-associated Lp-PLA2 activity and mass. METHODS AND RESULTS In 50 patients with Type IIA dyslipidemia were administered rosuvastatin (10 mg daily), where...