نتایج جستجو برای: hypsarrhythmia
تعداد نتایج: 120 فیلتر نتایج به سال:
Sleep and epilepsy have a close relationship. About 20% of patients suffer seizures only during the night, approximately 40% only during the day and approximately 35% during the day and night. In certain epilepsy syndromes, the occurrence of seizures is strongly related to sleep or awakening. Infantile spasms appear predominately on awakening, and hypsarrhythmia is sometimes visible only in sle...
Infantile spasms (IS) is the most recognized epileptic encephalopathy in early infancy, resulting in poor cognitive outcome. Adrenocorticotropic hormone (ACTH) therapy is the first-line therapy for IS, but the relapse rate is high. Relapse after initial ACTH therapy is a poor prognostic factor for longterm seizure control and outcome of cognitive function. Recently, several studies have reporte...
PurposeViral encephalitis (VE) or bacterial meningoencephalitis (BME) in early childhood may cause brain injury and neurological sequelae, including epilepsy. Postencephalitic epilepsy (PEE) characterized by epileptic spasms (ES) is a rare but serious condition; there an urgent need to develop new methods evaluate the characteristics of these children select appropriate treatments.MethodsWe con...
Early infantile epileptic encephalopathy or EIEE (Ohtahara syndrome; OS) is a kind of intractable seizure that begins in neonatal age with sudden onset of tonic spasms in series or single suppression-burst S-B in EEG. Imaging shows anatomic defects such as migration disorders and generalized atrophy with essentially normal metabolic tests. The seizures often change to West’s syndrome (WS) or Le...
patient. The other sister was living and well. The patient showed a slow progress in mental and motor function since the infancy. During the infancy she had often vomiting. There was no history of convulsions or severe illness. On admission at the age of 9 years, the patient showed mental retardation and motor dysfunction of severe degree. She was able to sit alone but unable to stand or walk. ...
West syndrome is a generalized epileptic syndrome of infancy, that is characterized by clinical spasms and hypsarrhythmia and usually has an onset age before two years old. Children affected by West syndrome have a high risk of severe psychomotor developmental delay. Infants with West syndrome without identification of underlying neurological disorder after adequate investigations are classifie...
Infantile spasms constitute both a distinctive seizure type and an age-specific epilepsy syndrome that have been extensively described for over a century. Standardization of the classification of infantile spasms has evolved, culminating in recent recommendations for separately recognizing and distinguishing the seizure type (spasms or epileptic spasms) and the epilepsy syndrome of infantile sp...
OBJECTIVE To report the follow-up findings of 7 children with severe epilepsy as a result of thiamine deficiency in infancy caused by a defective soy-based formula. METHODS The medical records of 7 children aged 5-6 years with thiamine deficiency in infancy who developed epilepsy were reviewed and their clinical data, EEG tracings, and neuroimaging results were recorded. The clinical course a...
PURPOSE To investigate the efficacy of topiramate monotherapy in West syndrome prospectively. METHODS The study population included 28 patients (15 male and 13 female children aged 2 to 18 months) diagnosed with West syndrome. After a 2-week baseline period for documentation of the frequency of spasms, topiramate was initiated at 2 mg/kg/day. The dose was increased by 2 mg/kg every week to a ...
Migrating partial seizures of infancy, also known as epilepsy of infancy with migrating focal seizures, is a rare early infantile epileptic encephalopathy with poor prognosis, presenting with focal seizures in the first year of life. A national surveillance study was undertaken in conjunction with the British Paediatric Neurology Surveillance Unit to further define the clinical, pathological an...
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