OBJECTIVE Expression of adhesion molecule receptors on venous endothelial cells crucially influences the fate of venous grafts by mediating leukocyte-endothelium interactions. These interactions include adhesion of leukocytes to the endothelium, followed by transendothelial migration, leading to neointimal hyperplasia (NIH) and finally graft occlusion. Therefore, inhibition of adhesion molecule...

Transcriptome analyses were conducted on the ileal mucosa of 14- to 35-day-old piglets to investigate postnatal gut development during suckling and postweaning. The transcriptome profiles of 14-day-old suckling piglets showed a considerably higher number of differentially expressed genes than did those of 21-, 28-, and 35-day olds, indicating an intensive gut development during the first 14-21 ...

In a previous work we applied a discrete symmetry (Z ′ 2) in order to light fermions acquire mass only at one loop level. This symmetry and the assumption of alignment between fermions and sfermions allow us to avoid FCNC problems. Here a more general hypothesis of flavor mixing in the sfermion sector of MSSM is considered and we show that the s quark is heavier than u, d quarks due to differen...

BACKGROUND New epithelial cells are generated through the proliferation and differentiation of resident progenitor cells in the nasal cavity. In several upper airway diseases, such as cystic fibrosis and chronic rhinosinusitis, self-renewing progenitor cells may be functionally defective, or compromised in their ability, to regenerate cells that maintain normal mucociliary clearance. Herein, we...

Object Aneurysmal subarachnoid hemorrhage triggers an intense inflammatory response, which is suspected to increase the risk for secondary complications such as delayed cerebral ischemia (DCI). However, to date, the monitoring of the inflammatory response to detect secondary complications such as DCI has not become part of the clinical routine diagnostic. Here, we aim to illustrate the time cou...

OBJECTIVE To examine whether the psychological traits of hopelessness and depressive symptoms are related to endothelial dysfunction. METHODS Data are derived from a subsample of 434 respondents in the 2001 to 2003 Chicago Community Adult Health Study, a population-based survey designed to study the impact of psychological attributes, neighborhood environment, and socioeconomic circumstances ...

We study the effects of tree-level flavor changing neutral current and its present status with Cabibbo-Kobayashi-Maskawa matrix. Especially, we remark the effects of flavor changing neutral current on the unitary triangle of Cabibbo-Kobayashi-Maskawa matrix. In the case when the unitarity is nearly conserved, we find that the allowed FCNC in the db sector is zd db /V CKM td V CKM tb * ∼ O(10 −2...

Background Alzheimer's disease (AD) is the most common type of dementia, which brings tremendous burden to sufferers and society. However, ideal tactics are unavailable for AD. Our previous study has shown that CZ2HF, a Chinese herb preparation, mitigates cognitive impairment in AD rats; whereas, its detailed mechanism not been elucidated. Methods Public databases were applied collect identify ...

We construct explicit examples with a horizontal, " anomalous " U (1) gauge group, which, in a supersymmetric extension of the standard model, reproduce qualitative features of the fermion spectrum and CKM matrix, and suppress FCNC and proton decay rates without the imposition of global symmetries. We review the motivation for such " more " minimal supersymmetric standard models and their predi...