Background Patients with beta thalassemia suffer from increased susceptibility to infections and putridity plays a major role in the patient's morbidity and mortality. The risk of transfusion-transmitted viral infection is well known in these patients. However, there is dearth of information about the seroprevalence of herpes simplex virus (HSV) infection in patients with beta thalassem...

Background: Anticardiolipin (ACL) antibodies are associated with a wide variety of disorders including malignancies. The aim of this study was to investigate the prevalence and prognostic implication of ACL antibodies in patients with Non-Hodgkin’s lymphoma (NHL). Methods: Sixty-four patients with NHL were included in this study. Enzyme-linked immunosorbent assay kits were used to measure the c...

BACKGROUND Patients with Irritable Bowel Syndrome (IBS) often relate their symptoms to the intake of food and modify their diet. IgE-mediated food allergy is uncommon in IBS, but the role of IgG-mediated food hypersensitivity remains inconclusive. The primary aim of this study was to compare food- and yeast-specific IgG and IgG4 antibodies in subjects with and without IBS. METHODS This was a ...

BACKGROUND Sodium aurothiomalate has been reported to have in vitro activity against Helicobacter pylori. Intramuscular gold, as given to patients with rheumatoid arthritis (RA), may therefore influence the colonisation of the gastric mucosa with H pylori. METHODS Two groups were compared. One group of 42 patients was treated with intramuscular gold; the other group of 58 patients was treated...

The anterior eye chamber is called the immunologically privileged place. The inflammatory disturbances in the interior of the eye chamber are characterised primarly by the changes of the IFN-gamma, IgG and IL-4 concentration and appearance of the oligoclonal IgG. In type I diabetes, there are antibodies to the beta cells of the pancreas, IgG class (among others such as antiretinal antibodies) a...

PURPOSE Immune system of some autistic patients could be abnormally triggered by gluten/casein assumption. The prevalence of antibodies to gliadin and milk proteins in autistic children with paired/impaired intestinal permeability and under dietary regimen either regular or restricted is reported. METHODS 162 ASDs and 44 healthy children were investigated for intestinal permeability, tissue-t...

Anti-glycan antibodies are an abundant subpopulation of serum antibodies with critical functions in many immune processes. Changes in the levels of these antibodies can occur with the onset of disease, exposure to pathogens, or vaccination. As a result, there has been significant interest in exploiting anti-glycan antibodies as biomarkers for many diseases. Serum contains a mixture of anti-glyc...

--Non-precipitating antibodies localized in the IgG,, IgGb and IgGc were isolated from serum of horses inoculated with DNP-HGG, with or without anti-DNP precipitins. The methods for isolation and purification of precipitating and non precipitating antibodies are described. The physicochemical characteristics and biological properties of precipitating and non-precipitating antibodies localized i...

The prevalence of anticardiolipin antibodies was evaluated in 70 children with juvenile chronic arthritis (JCA), in 25 adult patients with rheumatoid arthritis, in 42 healthy children and in 40 adult controls. Thirty seven (53%) patients with JCA were positive for IgG or IgM anticardiolipin antibodies, or both, and 30 (43%) for IgG anticardiolipin antibodies. In contrast, only seven (28%) adult...