The complete DNA sequence of the avian adenovirus chicken embryo lethal orphan (CELO) virus (FAV-1) is reported here. The genome was found to be 43,804 bp in length, approximately 8 kb longer than those of the human subgenus C adenoviruses (Ad2 and Ad5). This length is supported by pulsed-field gel electrophoresis analysis of genomes isolated from several related FAV-1 isolates (Indiana C and O...

The composition of an evolving arterial thrombus may be a determinant of how effectively pharmacologic agents prevent reocclusion after initially successful thrombolysis. In this study, reoccluding plateletor fibrin-rich thrombi as delineated by scanning electron microscopy were produced selectively in the femoral arteries of dogs with the use of electrically induced vascular injury or implanta...

The secretory and aggregation responses of stirred platelets exposed to complement proteins C5b-9 was investigated. C5b-9 assembly on the platelet surface resulted in the release of dense granule adenosine triphosphate (ATP) accompanied by a decrease in sample turbidity. but no detectable cell lysis. Inhibition of cellular protein kinase C completely blocked the C5b-9 initiated release of ATP. ...

Á unglingsárum takast einstaklingar á við ýmsar breytingar og áskoranir. Góð andleg líðan er forsenda velferðar fólks því vekur það áhyggjur að henni fer hrakandi hjá ungmennum Vesturlöndum. Áhyggjur beinast einnig vímuefnaneyslu ungmenna en sífellt koma fram nýjar áskoranir í efni. Markmið rannsóknarinnar var kortleggja andlega skoða samband þessara þátta gæði tengsla foreldra kyn. Einnig átti...

Chronic immune thrombocytopenic purpura (ITP) is an autoimmune disorder in which autoantibodies, most commonly against either the platelet glycoprotein (GP) IIb/Illa and/or GP Ib/lX complex, result in severe thrombocytopenia. Lasting complete and partial remissions are obtained in about 75% ofpatients with corticosteroids or splenectomy; refractory patients are usually treated with a variety of...

Greinin sem hér birtist byggir á gögnum um sveitakennara í tveimur sýslufélögum við Húnaflóa; Strandasýslu og Húnavatnssýslu, áður en formlegri skólaskyldu var komið á. Á Þjóðskjalasafni eru varðveittar fræðsluskýrslur frá 1887 vegna styrkumsókna veita þær dýrmætar upplýsingar hægt er að nýta til margvíslegra athugana. Í rannsókninni kynnt áhersla lögð grafast fyrir þá einstaklinga önnuðust ken...

Background. Plasmin has been reported both to activate platelets and to inhibit platelet functions. The latter effect was thought to be caused by proteolysis of the main membrane glycoproteins. Methods and Results. We found that incubation of citrated human platelet-rich plasma with streptokinase (SK) (300 IU/ml) does not produce any detectable activation but leads to a time-dependent inhibitio...

The pharmacodynamics of intravenous bolus injections of 0.05, 0.10, 0.15, and 0.20 mg/kg of F(ab')2 fragments of the murine monoclonal antibody 7E3, 7E3-F(ab')2, directed against the glycoprotein Ilb/Illa (GPIIb/IIIa) receptor of human platelets, were studied in groups of four patients with unstable angina pectoris. With 0.20 mg/kg, the template bleeding time prolonged from 6.3±1.9 (mean±SD) to...

In Islamic jurisprudence, the issue of relationship between cause and judgement, which is main pillar qiyas, accepted as most common way extending ruling nass, a subject that has theoretical aspect well practical aspect. Since third century Hijri, when methodology jurisprudence began to be codified, there have been different considerations regarding nature cause. This issue, was influenced by t...