Background: A system based on the B-cell phenotype has recently been proposed to classify patients suffering from common variable immunodefi ciency (CVID). Immunophenotypic T-cell abnormalities have also been correlated with clinical fi ndings, although they have never been used in classifi cation strategies. Objective: To simultaneously assess T and B-cell subset abnormalities in CVID patients...

1Department of Pediatric Hematology/Oncology, Mofi d Children Hospital, Shahid Beheshti Medical University, Tehran, Iran 2Molecular Immunology Research Center; and Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran 3Research Center for Immunodefi ciencies, Pediatrics Center of Excellence, Children’s Medical Center, Tehran University of Medical Scie...

INTRODUCTION Highly active antiretroviral therapy (HAART) has greatly changed the epidemiology of human immunodefi ciency virus (HIV) mortality. The aim of this study is to compare the causes of death and factors associated with early death in HIV-infected persons in the pre- and peri-highly active antiretroviral therapy (HAART) periods. MATERIALS AND METHODS We conducted a retrospective revi...

BACKGROUND The paper presents the intentional use of biological agents for industrial, diagnostic and research purposes in Polish enterprises. MATERIAL AND METHODS The National Register of Biological Agents (Krajowy Rejestr Czynników Biologicznych - KRCB) is an online database that collects the data on the intentional use of biological agents at work in Poland. RESULTS As of December 2013 t...

E ciency is considered a key factor when evaluating a bank's performance. Moreover, e ciency enhancement is an explicit policy objective in the Single Market Directive of the European Commission. But e ciency improvements may come at the expense of deteriorating bank pro ts and excessive risk-taking. Both the quantitative e ects and dynamic reactions of performance in response to e ciency impro...

during the last years, the concept of input congestion and technical ineff-ciency in data envelopment analysis (dea), have been investigated by manyresearchers. the motivation of this paper is to present models which obtain thedecreased output value due to input congestion and technical ineciency. more-over, we extend the models to estimate input congestion, technical ineciencyand output red...

This paper introduces, for an experimental design with design matrix X; the optimal design criterion based on the expectation of the square root of the quadratic form u(XX)u. This provides a geometric and statistical measure of the size of a con ̄dence ellipsoid, namely, the expected radius of an ellipsoid. Properties of the criterion are derived and examples are given to demonstrate the procedu...

A conceptual framework for crop production effi ciency was derived using thermodynamic effi ciency concept, in order to generate a tool for performance evaluation of agricultural systems and to quantify the interference of determining factors on this performance. In Thermodynamics, effi ciency is the ratio between the output and input of energy. To establish this relationship in agricultural sy...