نتایج جستجو برای: immunoglobulin deficiencies

تعداد نتایج: 89143  

Journal: :Deutsches Aerzteblatt Online 2010

Journal: :The Turkish journal of pediatrics 2005
Benan Bayrakci Fügen Ersoy Ozden Sanal Sebnem Kiliç Ayşe Metin Ilhan Tezcan

Immunoglobulin replacement therapy is the essential treatment of B-cell deficiencies. Because of the high expense of therapy, optimal dose, infusion intervals and serum IgG levels should be well defined. Data of 19 X-linked agammaglobulinemia (XLA), 7 hyper-IgM syndrome (HIM) and 20 common variable immunodeficiency (CVID) patients were analyzed. Infection frequencies and hospitalization require...

Journal: :archives of razi institute 2016
m.h. motedayen g. nikbakht m.j. rasaee a. zare mirakabadi

human snake bitten poisoning is a serious threat in many tropical and subtropical countries such as iran. the best acceptable treatment of envenomated humans is antivenoms; however they have a series of economic and medical problems and need more improvements. in this study a combinatorial human immunoglobulin gene library against some of iranian snakes venoms was constructed. total rna prepare...

2015
Sara Brito Kyle Thompson Jaume Campistol Jaime Colomer Steven A. Hardy Langping He Ana Fernández-Marmiesse Lourdes Palacios Cristina Jou Cecilia Jiménez-Mallebrera Judith Armstrong Raquel Montero Rafael Artuch Christin Tischner Tina Wenz Robert McFarland Robert W. Taylor

[This corrects the article on p. 102 in vol. 6, PMID: 25852744.].

Journal: :Biophysical journal 2010
Kingshuk Ghosh Ken Dill

Biological cells are extremely sensitive to temperature. What is the mechanism? We compute the thermal stabilities of the whole proteomes of Escherichia coli, yeast, and Caenorhabditis elegans using an analytical model and an extensive database of stabilities of individual proteins. Our results support the hypothesis that a cell's thermal sensitivities arise from the collective instability of i...

Journal: :Nucleic acids research 1991
S Kenwrick P Bridge D Lillicrap A E Lehesjoki J Bainton J Gitschier

References: l)Nussbaum,R.L., Airhart,S.D. and Ledbetter.D.H. (1986) Am. J. Med. Genet. 23, 457-466. 2)Patterson,M.N., Bell,M.V., BloomfieldJ,, Flint,T., Dorkins.H., Thibodeau.S.N., Schaid,D., Bren,G., Schwartz,C.E., Wieringa,B., Ropers,H.-H., Callen.D.F., Sutherland.G., Froster-Iskenius.U., Vissing.H. and Davies,K.E. (1989) Genomics 4, 570-578. A Taql polymorphism adjacent to the factor VIII ge...

2012
Randolph Hampton Martin Hetzer

Abstract: Aging is associated with the accumulation of misfolded and damaged proteins. This accumulation is the result of an imbalance of proper protein folding, maintenance, and disposal. Maintaining proteostasis is critical to the health and life of an organism. While studies consistently observe that the proteostasis network diminishes with age, the effects on individual mechanisms have not ...

2015
MM Esser

Selective IgA deficiency (IgAD) is the most common primary genetic immune defect, with high prevalence in Western countries and relatively low prevalence in the East. The laboratory definition of IgAD is based on the measured serum component. However, the important manifestations of deficiency of IgA, the most prevalent of human antibodies, relate to the absence of secretory IgA, which covers a...

Journal: :Clinical and diagnostic laboratory immunology 2004
I R Peters E L Calvert E J Hall M J Day

Selective immunoglobulin A (IgA) deficiency is the most common primary immunodeficiency in humans and may be associated with chronic gastrointestinal disease. This observation has led to the suggestion that the high susceptibility of German shepherd dogs (GSD) to chronic enteropathies is related to a deficiency in mucosal IgA production. Relative deficiencies of IgA has been reported in the ser...

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