Biochemical analysis and immunohistochemical techniques support the theory that hyperamylasaemia in lung cancer is due to amylase production in carcinoma cells. The vast majority of amylase-producing carcinomas are adenocarcinomas with amylase isoenzyme similar to the salivary type. This prospective study assesses alpha-amylase expression in resectable lung cancer. Seventy four patients with re...

BACKGROUND The liver is the most frequent site of metastatic disease, and metastatic disease to the liver is far more common than primary liver carcinoma in the United States. Pathologic evaluation of biopsy samples is key to establishing a correct diagnosis for patient management. Morphologic and immunoperoxidase studies, which are the standard for pathologic practice, accurately classify most...

Case Description and Clinical Findings- A seven-year-old male German shepherd dog was referred to Small Animal Clinic with severe lameness (non-weight-bearing) and considerable localized proximal right humerus swelling. Radiographic study revealed severe soft tissue swelling and pathologic fracture of proximal right humerus. Immediately, the right forelimb was removed surgically and once sample...

Cancer Control 219 detailed diagnostic and prognostic categorization. Recently published gene expression and proteomic profiling data indicate new candidate molecules involved in melanoma pathogenesis, which are currently validated. This ongoing process of biomarker identification and validation results in a rapidly changing molecular view and classification of cutaneous malignancies, which hol...

CAM 5.2 is a murine monoclonal antibody, raised against the colon carcinoma cell line HT29, which recognises lower molecular weight intracellular cytokeratin proteins within secretory epithelia. Extensive indirect immunohistochemical studies have confirmed that this antibody stains formalin fixed (and freshly frozen) normal and malignant human tissue in a consistent manner. Reliable staining of...

Solitary fibrous tumor is an uncommon neoplasm affecting adults and typically located in the pleura and can also occur in a large number of other extra thoracic sites. We present the case of a solitary fibrous tumor (SFT) of the retroperitoneum and describe their histopathological and immunohistochemical features. The identification of SFT in the retroperitoneum is of importance because its cli...

background in surgical pathology, atypical small acinar proliferation is commonly detected in prostate biopsies. most studies on atypical small acinar proliferation have examined morphological characteristics and the utility of immunohistochemical studies.however, these resources are not available to many pathology departments. we have found that examining additional sections is a simple and in...