The mortality for dogs with severe immune-mediated hemolytic anemia (IMHA) is unacceptably high, and better immunosuppressive regimens are needed to increase survival. Understanding the basic immunology of the disease and the mechanisms of action of the available immunosuppressive therapies will help clinicians choose an appropriate immunosuppressive protocol. Prospective, randomized clinical s...

1. Justify the rationale for using multiple drug regimens in recipients of solid organ transplants. 2. Analyze the limitations of established immunosuppressive strategies. 3. Evaluate the relative benefits and risks of withdrawal and avoidance immunosuppressive strategies. 4. Design and implement immunosuppressive strategies aimed at decreasing toxicity and improving long-term patient outcomes....