Thc N T T T Linguistic String 1>arscr (1,SI') is a ~vorldng system for the syntactic analysis of Ehglish scicntifie tests. It consists of a parsing program, a large-coverage b~glish grammar , and a Icsicon. Thc gramnlarls effcctivcncss in parsing texts is due in large part to a substantial Imdy of detail cvl \vc.Il-formedness rcst rictions which eliminate most incorrect syntactic parses which w...

How RNA-binding proteins recognize specific sets of target mRNAs remains poorly understood because current approaches depend primarily on sequence information. In this study, we demonstrate that specific recognition of messenger RNAs (mRNAs) by RNA-binding proteins requires the correct spatial positioning of these sequences. We characterized both the cis-acting sequence elements and the spatial...

The Cox2 subunit of Saccharomyces cerevisiae cytochrome c oxidase is synthesized in the mitochondrial matrix as a precursor whose leader peptide is rapidly processed by the inner membrane protease following translocation to the intermembrane space. Processing is chaperoned by Cox20, an integral inner membrane protein whose hydrophilic domains are located in the intermembrane space, and Cox20 re...

YB~,CLI,O,-~ thin films deposited by pulsed laser deposition were patterned by ion implantation. The pa~terning technique is based on the local disordering of the crystal structure due to elastic collisions of the imp1,mted 0'"-ions and thus . on a strong breakdown of superconductivity in the irradiated areas. With tkis patterning method circular and meandering structures with a size of 1 rnm w...

Prolonged carriage of Plasmodium fakiparum in humans during the dry season is critical for parasite survival, as the infected subjects constitute a major reservoir in the absence of transmission. Yet, very little is known about the host/parasite interactions contributing to parasite persistence. In order to study the characteristics of P. falclpamni infections during the dry season, we have gen...

Cancer sera contain antibodies which react with a unique group of autologous cellular antigens called tumor-associated antigens (TAAs). This study determines whether a mini-array of multiple TAAs would enhance antibody detection and be a useful approach to cancer detection and diagnosis. The mini-array of TAAs comprised full-length recombinant proteins expressed from cDNAs encoding c-myc, p53, ...

Compared with yeast, our knowledge on members of the ATP-independent plant mitochondrial proteolytic machinery is rather poor. In the present study, using confocal microscopy and immunoblotting, we proved that homologs of yeast Oma1, Atp23, Imp1, Imp2, and Oct1 proteases are localized in Arabidopsis mitochondria. We characterized these components of the ATP-independent proteolytic system as wel...