infantile haemangiomas (ih) are the most common vascular tumors occurring in early childhood, with a prevalence of approximately 5-10% of infants. these vascular tumors are divided into two main groups including infantile haemangioma and vascular malformations. although, haemangioma of infancy are common, benign and self-limited tumors, a significant percent of these lesions are associated with...

Abstract Background Infantile Fibrosarcoma is a rare soft tissue tumor in infants and children mostly located in extremities. An infantile and adult form has similar histopathological patterns but survival prognosis is much better in infantile form. Recurrence of infantile fibrosarcoma is common but the rates of metastasis are less than 10 percent in children younger than five Years and 50 p...

Background Infantile colic is a painful phase in the first months of infancy but no safe and effective conventional treatment exists. Massage is used in traditional medicine as a control and treatment method for infantile colic. The aim of this study is to evaluate the efficacy and safety of massage in the control and treatment of infantile colic. Materials and Methods We searched international...

dobutamine stress echocardiography (dse) has been widely used as a diagnostic and prognostic modality in the management of stress. dse is associated with limited complications and adverse effects on the health of patients. in this case report, we described a 42-year-old female patient with dobutamine-induced coronary artery spasm with history of exertional dyspnea, which had deteriorated recent...

BACKGROUND We reported less provoked spasm in the left circumflex artery (LCX) by acetylcholine testing compared with the left anterior descending artery (LAD) and right coronary artery (RCA), so we investigated the clinical characteristics of provoked spasm in the LCX by ergonovine (ER) testing.Methods and Results:We retrospectively analyzed 1,185 consecutive cases of intracoronary ER testing ...

Patients presenting with infantile spasms, dysmorphic features, and periventricular nodular heterotopia may benefit from genetic copy number variation microarray, or whole-exome sequencing to identify candidate genes. This will allow personalized diagnosis and prognostication and the eventual understanding of single and combined gene functions in brain health and disease.

BACKGROUND Radial artery spasm is a common hinderance during transradial approaches for neuroangiography. Ways of alleviation have been described, including patient sedation, local lidocaine, or even prophylactic administration intra‐arterial vasodilators. METHODS We present case wedged catheter attributable to radial spasm, which failed all conventional methods relieve spasm. RESULTS The was u...

Epilepsy is a neurological disease of the central nervous system. It is estimated that about 50-70 million people worldwide suffer from this chronic disorder and 20 to 30% are resistant to conventional anti-epileptic drugs. In the epilepsy therapeutic arena, there is real need for developing novel antiepileptogenesis treatments that offer a way to prevent the onset or the progression of the dis...

While >200 types of etiologies have been shown to be involved in the pathogenesis of infantile spasms, the pathophysiology of infantile spasms remains largely elusive. Pre-natal stress and hypothalamic-pituitary-adrenal axis dysfunction were shown to be involved in the development of infantile spasms. To test the genetic association between the CRHR1 gene, which encodes the corticotrophin-relea...