PURPOSE CD93 is receiving renewed attention as a biomarker of inflammation. We aimed to evaluate the potential for serum sCD93 to serve as a novel biomarker for allergic inflammation. MATERIALS AND METHODS We enrolled 348 subjects with an allergic disease [allergic rhinitis (AR), chronic spontaneous urticaria (CSU), or bronchial asthma (BA)], including 14 steroid-naïve BA patients who were se...

E vidence suggests that thrombosis, endothelial dysfunction and inflammation are strongly associated with coronary artery disease (CAD). Inflammation plays a crucial role in characterizing the formation of atheromatous plaque, as well as its progress.1-6 The secretion of proinflammatory cytokines from the vascular endothelium as well as from macrophages induces the production of inflammatory mo...

BACKGROUND Markers of immune activation have been associated with mania but have not been examined in combination. We studied the association between mania and an inflammation score based on four immune markers. METHODS A total of 57 individuals with mania were assessed at up to three time points: the day of hospital admission, evaluation several days later, and six-month follow-up. Also asse...

BACKGROUND Although procalcitonin (PCT) has been described as a new marker of infection and inflammation, it has not been extensively studied in dialysis patients. METHODS We measured plasma PCT levels in 62 patients on maintenance haemodialysis (30 M/32 F, age 61.8+/-17.1 years, on dialysis for 75+/-93 months, 12 h/week, with a Kt/V of 1.53+/-0.31, high-flux membrane being used in 25 patient...

C-reactive protein (CRP) is a major acute phase protein in dogs. Its concentration increases rapidly and significantly during systemic inflammation and subsequently decreases quickly following the elimination of the source of inflammation. Kinetics of canine CRP (cCRP) in an acute phase response are similar to those of human CRP. The synthesis of CRP in hepatocytes is induced by inflammatory cy...

1Departments of Neurology, Singapore General Hospital, National Neuroscience Institute 2Duke-NUS Graduate Medical School, Singapore Address for Correspondence: Assoc Prof Eng King Tan, Department of Neurology, Singapore General Hospital, Outram Road, Singapore 169608. Email: [email protected] Parkinson’s disease (PD) is a common neurodegenerative disease which frequently leads to neurological d...

BACKGROUND Cigarette smoking is a classical and a major risk factor in the development of several diseases with an inflammatory component, including cardiovascular disease and chronic obstructive pulmonary disease. Improvements in assays for protein markers of inflammation have led to many studies on these factors and their roles in disease. AIMS C-reactive protein (CRP) is one such marker an...

Paraoxonase 1 (PON1) and serum amyloid A (SAA) are proteins carried by high-density lipoprotein (HDL) particles. Among the HDL-associated protein molecules, SAA, an inflammation-related marker, and PON1, an antioxidant marker, tend to change in relatively clear opposite directions in physiological situations. In clinical chemistry, paired measurements of both markers may provide useful informat...

Abstract Smoking is a severe health problem. has been shown to increase the risk of systemic inflammation. Neutophil Lymphocyte Ratio (NLR) used as marker inflammation and monitors prognosis, morbidity, mortality in many diseases. This study aimed analyze NLR smokers. an observational analytic conducted at Tadulako University, Palu. A total 48 subjects consisted 24 active smokers non-smokers. S...