BACKGROUND Non-steroidal anti-inflammatory drugs have been implicated in reports of liver injury. However, the precise risk of non-steroidal anti-inflammatory drugs for this rare complication is unknown. AIM To review systematically the published literature of population-based epidemiological studies reporting the incidence or comparative risk of non-steroidal anti-inflammatory drugs for live...

A series of five-membered heterocyclic rings were synthesized by the reaction between benzoyl chloride and various chlolro-nitro-benzoyl chlorides and semi carbazide to form (C1-C7) compounds and was tested for their anti-inflammatory activity determined by rat-paw-oedema method. All the synthesis compounds have been characterized by 1HNMR, IR and Mass spectral data. The compounds were purified...

Nonsteroidal anti-inflamatory drugs (NSAIDs) and glucocorticoids, nowaday are the main groups of anti-inflamatory drugs in modern pharmacology. The side effects of these antiinflamatory drugs, specially using in chronic diseases cause many problems for the patients and the physicians, so finding the new anti-inflamatory drugs with less side effect is the aim of many researchers. WHO emphasiz to...

Nonsteroidal anti-inflamatory drugs (NSAIDs) and glucocorticoids, nowaday are the main groups of anti-inflamatory drugs in modern pharmacology. The side effects of these antiinflamatory drugs, specially using in chronic diseases cause many problems for the patients and the physicians, so finding the new anti-inflamatory drugs with less side effect is the aim of many researchers. WHO emphasiz to...

objective: pain control in dentistry especially endodontics is particularly important. endodontic pain following root canal therapy (rct) of vital teeth is closely correlated with inflammatory reactions. increased level of prostaglandins has been reported in acute inflammatory reactions. thus, cyclooxygenase-inhibiting drugs have a significant effect on reducing pain and inflammation. cox enzym...

Neuro-inflammation is a reaction to brain injury involving the activation of glial cells and release of inflammatory mediators, such as cytokines and chemokines which has a key role in neuro-degenerative diseases. Periodontitis is a microbiome-related dental inflammation caused by gram- negative bacteria that leads to connective tissue destruction and loss of teeth. Previous studies demonstrated...