Hypothesis / aims of study The interstitial cells of Cajal (ICC) are primary pacemaker cells responsible for generating smooth muscle activity in the gastrointestinal tract. ICCs express the proto-oncogene c-kit, 3 and signaling via the receptor kinase gene product, KIT, is essential for the development of phenotype and rhythmicity. ICC-like cells form close connections with suburothelial nerve...

BACKGROUND Constrictive vascular remodeling (VR) is the most significant component of restenosis after balloon angioplasty (PTA). Whereas in physiological conditions VR is associated with normalization of shear stress (SS) and wall stress (WS), after PTA the role of SS and WS in VR is unknown. Furthermore, whereas matrix metalloproteinase inhibition (MMPI) has been shown to modulate VR after PT...

Williams syndrome (WS) is a neurodevelopmental condition that occurs as a result of a contiguous deletion of ∼26-28 genes on chromosome 7q11.23. WS is often associated with a distinctive social phenotype characterized by an increased affinity toward processing faces, reduced sensitivity to fear related social stimuli and a reduced ability to form concrete social relationships. Understanding the...

background: we investigated the effects of withania somnifera root (ws) on insulin resistance, tumor necrosis factor α (tnf-α), and interleukin-6 (il-6) in fructose-fed rats. methods: forty-eight wistar-albino male rats were randomly divided into four groups (n=12); group i as control, group ii as sham-treated with ws by 62.5mg/g per diet, group iii fructose-fed rats received 10%w/v fructose, a...

As a two-dimensional semiconductor, WS₂ has attracted great attention due to its rich physical properties and potential applications. However, it is still difficult to synthesize monolayer single-crystalline WS₂ at larger scale. Here, we report the growth of large-scale triangular single-crystalline WS₂ with a semi-sealed installation by chemical vapor deposition (CVD). Through this method, tri...

this study was carried out to investigate the effects of 1, 25-dihydroxycholecalciferol (1, 25 (oh)2 d3) and root hydroalcoholic extract of withania somnifera (ws) root on performance, mineral retention, bone mineralisation and mechanical characteristics of broiler chicks. treatments were arranged factorially (2×3×2) consisted of a positive control with adequate ca and a negative control diet (...

Wheat straw (WS) was pretreated with four concentrations of H2O2 (1%, 2%, 3%, and 4%) and was anaerobically codigested with dairy cattle manure (CM) at various ratios from 100:0 to 0:100. Wet-state H2O2 pretreatment effectively enhanced the biodegradability and methane yield of the WS. The optimal concentration of H2O2 for treating WS was 3%. The methane yield was higher with the codigestion of...

The OASIS web services security (WSS) standard has been developed to provide encryption and digital signing for SOAP messaging to ensure the information in the message is confidential and that the sender and receiver are who they say they are. It has also introduced interoperability and performance problems. Interoperability has been improved with the introduction of the WS-I* Basic and Basic S...

Werner syndrome (WS) is a rare autosomal-recessive disorder characterized by the premature appearance of features of normal aging in young adults. The extensive phenotypic overlap between WS and normal aging suggests they may also share pathogenetic mechanisms. We reported previously that somatic cells from WS patients demonstrate a propensity to develop chromosomal aberrations, including trans...