Abstract Background Intrathecal (IT) catheter delivery of baclofen via continuous infusion using an implantable pump is important means treating patients with severe spasticity. We evaluated the impact IT tip placement (upper vs. lower) on brain and spine distribution a radioactive tracer molecule. Methods Cynomolgus monkeys were implanted catheter, distal located at either C1 or T10 attached t...

This case study summarizes the systems engineering aspects of the next-generation SymbiqTM IV (intravenous) medical pump development. SymbiqTM was developed by Hospira Inc. and documented in detail in Chapter 5 of the National Research Council book, Human-System Integration in the System Development Process. As described in the book, SymbiqTM's purpose was “to deliver liquid medications, nutrie...

Background: The specialized registered nurses working in the technologic homecare team of our organization are highly qualified in technical nursing. One component of their job is the intravenous administration of medication to patients in their own home by using an infusion pump. In a hospital setting you can ask a colleague nurse to check the installation of the pump and the dose of medicatio...

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At the time of discharge, recovery room nurses discontinued the infusion through the epidural so that the infusion could be started in the ward through the ward infusion pump. In the ward, the recovery room nurses handed over the patient to the ward technician. The ward technician unknowingly connected the infusion to the intravenous cannula and started the infusion at 1930 hrs. At 0500 hrs the...

We studied how lowering a syringe pump and changing the outflow pressure could affect syringe pump output. We experimentally reduced the height of three different syringe pump systems by 80 cm (adult setting) or 130 cm (neonatal setting), as can happen clinically, using five flow rates. We measured the time of backward flow, no flow and the total time without flow. An exponential negative corre...

tranexamic acid is now used on a routine basis for on-pump coronary artery bypass grafting (cabg). we assessed the hemostatic effects of tranexamic acid to decrease bleeding tendency and transfusion requirements in patients undergoing off-pump coronary artery bypass surgery (opcab). a total of 66 patients were enrolled to elective opcab in a double-blind, prospective randomized study. of these,...

Insulin treatment can lead to local soft tissue dystrophies. We present the cases of two insulin-treated subjects with two different injecting systems: a basal/bolus and a continuous subcutaneous insulin infusion (insulin pump). The local cutaneous/subcutaneous dystrophies adversely affected their glycaemic values. A conventional and a high resolution ultrasound (20MHz Dermascan) were used to a...

Background: Local infiltration analgesia pumps have been increasingly used to provide postoperative pain relief. However, their flow rate over time may not be reliable and accurate which can pose concerns regarding the achievement of the desired therapeutic level. We sought to find out in vitro if the flow rate of two elastomeric infusion pumps when combined with two types of wound catheter is ...