At the time of discharge, recovery room nurses discontinued the infusion through the epidural so that the infusion could be started in the ward through the ward infusion pump. In the ward, the recovery room nurses handed over the patient to the ward technician. The ward technician unknowingly connected the infusion to the intravenous cannula and started the infusion at 1930 hrs. At 0500 hrs the...

OBJECTIVE To compare the clinical safety of the rapid infusion of infliximab (30-45 min) with the traditional one (2 h). PATIENTS AND METHOD Open, prospective study with the consecutive inclusion of 150 patients with rheumatoid arthritis (RA) and/or spondyloarthritis (AS), resistant to conventional treatment. Patients were randomly distributed to receive 1.5 or 3 mg/kg (according to medical c...

PURPOSE Intravenous (IV) zoledronic acid (ZA) is commonly used to delay skeletal complications secondary to bone metastases. However, the time associated with ZA administration may represent a significant burden to healthcare providers and patients. This study assessed the time associated with IV ZA infusion in patients with bone metastases secondary to breast or prostate cancer (BC or PC) in t...

Oxaliplatin, established as a therapeutic standard globally for advanced/recurrent colorectal cancer, was approved in Japan in April 2005. With this approval the FOLFOX and FOLFIRI regimens are often selected now as 1st or 2nd line treatment for advanced/recurrent colorectal cancer. Patients receiving these regimens needed to be hospitalized, because the total treatment period was as long as 48...

Background: The effective therapeutic dose of pralidoxime methylsulphate for organophosphate (OP) poisoning is necessary to be clarified. This study was designed to comparatively assess the blood level of pralidoxime (BPL) and clinical outcomes in OP poisoned patients treated with intermittent dosing and patients treated with continuous infusion. Methods: This was a prospective, open labelled, ...

In this study, purple basil leaves were dried in 3 different methods (oven, microwave, and shade drying) then infused 5 times hot water at 90 oC. Analyses of total phenolic content, antioxidant activity, monomeric anthocyanin color parameters performed on tea samples. When the analysis results evaluated, best determined samples prepared from oven shade, brewing 10 15 minutes. 45 minutes was inf...