BACKGROUND Vaccine use has been increasing worldwide, and adult populations are presented with more opportunities to experience pain from vaccine injection. The insertion of a needle through the skin is the most common source of iatrogenic pain, and needle phobia is a major concern in medical practice. However, it is unclear which factors play major roles in the perception of pain from vaccine ...

OBJECTIVE The purpose of this prospective, randomized, blinded study was to compare the pain of injection and post-injection pain of the AMSA injection using the computer-assisted Wand Plus injection system versus a conventional syringe. STUDY DESIGN Using a crossover design, 40 subjects randomly received 2 blinded AMSA injections using the Wand Plus system and a conventional syringe, at 2 se...

The objective of this open, multicentre, randomized controlled study in women opting for in-vitro fertilization was to compare the occurrence of pain and redness at the injection site and of post-injection fever after i.m. injection with Humegon (n = 89) or Pergonal (n = 92). Assessments were scoring of pain and redness at the injection site and of post-injection fever during the next 24 h usin...

Background and Aim: Local anesthetic injection is among the most anxiety-provoking procedures in children. Some scales are currently available to quantify the level of pain experienced based on the child’s behavior. The purpose of this study was to compare two commonly used pain scales. Materials and Methods: This split-mouth study was conducted on 49 healthy children aged 3.5 to 9 years who n...

Introduction: : It seems that Valeriana officinalis (valerian) extract through gamma-amino-butyric acid A (GABAA) receptor possesses analgesic effect. The aim of the present study was to investigate the effect of muscimol and picrotoxin on pain sensitivity in male rats pretreated with valerian extract using the formalin test. Methods: Thirty-five male rats weighing 200-250g in standard temp...

INTRODUCTION There has been a recent interest in injecting large body and face areas with local anesthetic in a minimally painful manner. The method includes adherence to minimal pain injection details as well feedback from the patient who counts the number of times he feels pain during the injection process. This article describes the successes and limitations of this technique as applied to p...

Background: Corticosteroid injections are used to treat a variety of orthopedic conditions with the goal of decreasingpain and inflammation. Administration of systemic or local corticosteroids risks temporarily increasing blood glucoselevels, especially diabetic patients. The purpose of this study is to quantify the effects of corticosteroid injections onblood glucose levels in diabetic patient...

background postoperative pain is considered as a reason of patient’s delay in discharge and disability aggravation. therefore, multimodal approaches have been suggested in order to mitigate pain and decrease postoperative side effects. objectives the aim of this study was to evaluate analgesic effect of a single dose injection of dexamethasone on reducing postoperative pain in laparoscopic chol...

objectives the aim of the present study was to assess and compare the efficiency of lidocaine 0.4% and 2% in reducing the incidence and severity of propofol injection pain. background propofol is one of common anesthetic drugs used in anesthesia. the most common side effects of propofol are local pain. pretreatment with lidocaine can reduce propofol injection pain. patients and methods this was...

59 backing, have come to assume the benefit afforded by these agents. Gill and Orr (1979) astonished the profession through their clinical trials which disclosed the absence of statistically significant difference in injection pain experienced by patients who were pretreated with topical anaesthetics and a placebo. This study was undertaken to confirm the validity or otherwise of the claim made...