نتایج جستجو برای: interferon beta 1b
تعداد نتایج: 269096 فیلتر نتایج به سال:
the aggregation of protein is the most prevalent and the most disturbing kind of instability and this challenge exists in almost every stage of the development of protein drug. the presence of insoluble aggregations in protein drugs will make the supply of the product a tough job. this study identifies the inhibition of the folded interferon beta 1-b’s aggregation with the assistance of some ex...
BACKGROUND There are no data on neutralising antibodies to interferon-beta and its clinical implications in Chinese patients with multiple sclerosis (MS). OBJECTIVES The objectives of this study were to investigate the prevalence of neutralising antibodies among Chinese patients with relapsing MS receiving interferon-beta (1a or 1b) and to study the association between neutralising antibodies...
OBJECTIVE To determine whether interferon therapy during human pregnancy increases reproductive risks in women. METHODS This longitudinal, controlled cohort study consisted of three groups of women: an exposed group, a disease matched unexposed group, and a healthy comparative group. Subjects were selected from women contacting the Motherisk Program regarding maternal beta interferon exposure...
multiple sclerosis (ms) is an inflammatory, multifocal, immune-mediated disease of the central nervous system that women are at a higher risk to acquire than men. myxovirus resistance protein a (mxa) is used as a predictive marker of bioactivity of interferon-beta (ifn-β) therapy in ms patients. this study was undertaken in west of iran to investigate gender differences in the expression level ...
Introduction: Based on data from recent trials, peginterferon and ribavirin combination therapy is the standard of care in treating patients with chronic HCV infection, but because of high costs, many patients may deprive from treatment. Methods: We conducted a clinical trial on HCV patients in Yazd in gastroenterology clinic. Thirty patients received conventional subcutaneous interferon alf...
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