Direct-acting antiviral (DAA) therapies have revolutionised the treatment of hepatitis C virus (HCV). The financial cost of DAAs however is significant, and first generation protease inhibitors (PIs) also require frequent monitoring of viral RNA levels to guide treatment. In this context, we examined the relevance of HCV antigen testing to evaluate the potential role in monitoring virological r...

The first general Zagreb index is defined as $M_1^lambda(G)=sum_{vin V(G)}d_{G}(v)^lambda$. The case $lambda=3$, is called F-index. Similarly, reformulated first general Zagreb index is defined in terms of edge-drees as $EM_1^lambda(G)=sum_{ein E(G)}d_{G}(e)^lambda$ and the reformulated F-index is $RF(G)=sum_{ein E(G)}d_{G}(e)^3$. In this paper, we compute the reformulated F-index for some grap...

Southern blot-hybridization analyses of human DNA (from Namalwa lymphoblastoid cells) digested with the restriction endonuclease EcoRI were carried out under optimal conditions with two human fibroblast interferon (IFN-beta 1) cDNA probes, pD19 and pD24, which contain IFN-beta 1 inserts 0.8 and 0.7 kilobase (kb) long, respectively. The analyses revealed the presence of several hybridizable DNA ...