background: inflammatory bowel disease, an autoimmune disease, has two clinical manifestations including crohn’s disease and ulcerative colitis (uc). il-17 has been the target of intensive research in autoimmune diseases. the influence of toll like receptor 4 (tlr-4) gene polymorphisms on il-17 production has also been revealed in uc patients and tissue inflammation in mice. objectives: to inve...

BACKGROUND: Psoriasis is frequently accompanied by metabolic syndrome. Effect of anti-tumor necrosis factor therapies on increases in body weight well-known. Data the effects interleukin-17 inhibitors are limited. Authors determined effect anti-interleukin-17 composition and serum lipid inflammatory parameters among severe psoriatic patients. METHODS: Thirty-five patients were enrolled. Twenty-...