DOI: 10.5935/abc.20140170 In this study, we report a case of a healthy, 25-year-old male patient with presyncope during a football match divergent blood pressure, and a grade 3/6 aortic diastolic murmur. The echocardiogram showed a rounded structure in the basal area of the interventricular septum adjacent to the aortic valve, which causes inadequate commissural support, communicating with the ...

Objective: To evaluate the relation between QT variables and disproportion of left ventricular wall hypertrophy in patients with hypertrophic cardiomyopathy. Design: Retrospective analysis of the results of echocardiography and electrocardiography. Setting: University hospital (tertiary referral centre). Patients: 70 patients with hypertrophic cardiomyopathy were divided into four groups accord...

BACKGROUND Aneurysm of the muscular interventricular septum is a rare entity as compared to the membranous part. Only a few cases of dissecting septal aneurysm have been reported in literature. Two-dimensional echocardiography is the initial diagnostic modality with ECG-gated CT and MRI being non-invasive imaging modalities for comprehensive evaluation. The complications can arise from chronic ...

Pulmonary arterial hypertension (PAH) causes pressure overload on the right ventricle and when untreated leads to progressive right ventricular dysfunction. Delayed contrast MRI can identify areas of myocardial infarction and myocardial fibrosis related to various cardiomyopathies. Delayed contrast magnetic resonance images in the short axis plane in 3 patients with PAH (Figure, A, idiopathic; ...

OBJECTIVE To evaluate the relation between QT variables and disproportion of left ventricular wall hypertrophy in patients with hypertrophic cardiomyopathy. DESIGN Retrospective analysis of the results of echocardiography and electrocardiography. SETTING University hospital (tertiary referral centre). PATIENTS 70 patients with hypertrophic cardiomyopathy were divided into four groups acco...

R UPTURE of the interventricular septum, one of the most dramatic complications of myocardial infaretion, has become a wellrecognized clinical entity that is readily confirmed by cardiac catheterization. Since the usual course is that of rapid deterioration and early death, surgical repair of the defect is indicated once the diagnosis has been established. The medical literature contains only a...

Mammalian Tolloid-like 1 (mTLL-1) is an astacin-like metalloprotease, highly similar in domain structure to the morphogenetically important proteases bone morphogenetic protein-1 (BMP-1) and Drosophila Tolloid. To investigate possible roles for mTLL-1 in mammalian development, we have used gene targeting in ES cells to produce mice with a disrupted allele for the corresponding gene, Tll1. Homoz...

Twent~-two patients with atrial septal defect (ostium secundum type and amua venosus) were studied by echucardiography before and after surgery. The sizes of the various heart chambers right and left ventricles, Ieft atrium and aortic root and the interventricular seprum and the left ventricular posterior free wall (motion and thickness) were analvsed and compared in the pre and postoperative p...

The results of damage to the heart from indirect violence have aroused a good deal of interest in recent years, for in many cases modern methods of investigation have increased the possibilities of diagnosis. The account of this unusual case seems worthy of record. A young man of nineteen years had a head-on collision with a lorry when driving a motor car. He was thrown forcibly against the ste...

Roger' in 1879 was the first to describe a congenital defect of the heart in which symptoms were absent, although definite, constant, and characteristic physical signs were present. An interesting feature of his description was that his observations were unsupported by an autopsy on the case that he described. However, so definite was the syndrome that Dupre", who verified a case at autopsy in ...