traumatic brain injury is a leading cause of disability and death from injury in the world. the interleukin-1 (il-1) is a family of cytokines that act as key mediators of the inflammatory response peripherally and centrally. based on many studies, researchers found that the il-1 is the well-known molecule in relation to acute tbi in the models of both focal and diffuse injuries. the il-1 family...

background hepatitis c virus (hcv) is a major cause of chronic liver disease worldwide. the role of intra familial hcv transmission is still controversial. the aim of the present study is to determine intra familial transmission (sexual and non sexual contacts) of hcv in a group of iranian population. patients and methods in this historical cohort study, 270 first degree relatives of hepatitis ...

objective: to determine the preventive effects of local administration of simvastatin for postoperative intra-abdominal adhesion formation in animal model of rat . methods: in this experimental study, 32 wistar albino rats as the animal model of intra-abdominal adhesion formation were included. adhesions were induced in all the animals via abrasion of the peritoneal and intestinal surface durin...

Osmotic minipumps were implanted chronically for continuous 11-d infusion of hypertonic sodium chloride (NaCl) into the third cerebral ventricle (ICV) of awake rats to determine whether baroreflex sensitivity would be altered. Systolic and mean pressures, recorded from aortic catheters on day 11 while the rats were anesthetized with alpha-chloralose, were significantly higher in rats infused wi...

knee surgery. the purpose of this study was to assess the analgesic effects of intra-articular injection of a dexmedetomidine following knee arthroscopy. methods:   forty six patients schadualed for arthroscopic knee surgery under general anaesthesia, were randomly devided into two groups. intervention group received 1μg/kg dexmedetomidine (d) and isotonic saline. control group received 25ml is...

conclusions although postoperative intra-articular meperidine is a better alternative for bupivacaine, their combination could improve their analgesic effects compared with each other alone. results the bupivacaine-meperidine group had better duration of postoperative analgesia (p = 0.001), latter first analgesic request (p ≤ 0.001), lower total fentanyl consumption in first 24 hours after the ...

introduction: acute pain and swelling following endodontic treatment are challenges for patients and dentists. according to previous studies, the incidence of flare-ups increases after endodontic treatment of teeth with necrotic pulp. calcium hydroxide is currently used as a multipotential medicament in root canal therapy. the aim of this study was to evaluate the incidence and severity of flar...

background: ovarian pregnancy is a rare form of the non-tubal ectopic pregnancy. it ends with rupture before the end of the first trimester. one of the important risk factors for ovarian pregnancy is in the use of intra uterine devices (iud). case:  we report here one such uncommon case of ovarian ectopic pregnancy. our patient is a 30 years old multiparous woman with two previous cesarean sect...