Local application of antibiotics within the root canal system may be a more effective mode for delivering the drug. Tetracyclines have been used to remove the smear layer from instrumented root canal walls, for irrigation of retrograde cavities during periapical surgical procedures, and as an intracanal medicament. Substantivity of tetracyclines has been shown for up to at least 12 weeks. BioPu...

Intracanal medications have historically played an important role in root canal therapy. Their purpose is to establish an antimicrobial environment within the pulp chamber (1). The root canal system may contain significant types and numbers of organisms that cause acute exacerbations, delay treatment procedures, and retard or prevent healing. Although mechanical instrumentation and frequent irr...

Endodontic posttreatment pain remains to be a significant problem facing the dental profession. Antibacterial intracanal dressing has been advocated to eliminate remaining bacteria after chemomechanical preparation.1 Various intracanal medicaments are advocated to eliminate bacteria and prevent multiplication of bacteria between the appointments. Calcium hydroxide (CH) has been the most commonl...

The authors reviewed the literature evaluating the antibacterial effectiveness of intracanal medicaments used in the management of apical periodontitis. A PICO (problem, intervention, comparison, outcome) strategy was developed to identify studies dealing with calcium hydroxide, phenolic derivatives, iodine-potassium iodide, chlorhexidine, and formocresol. The final inclusion/exclusion criteria...

An important consideration in endodontic treatment is the elimination of microorganisms, including fungi, from the complex threedimensional root canal system. Yeasts can be detected in 7-17% of infected root canals. Candida albicans (CA) has a major role in endodontic treatment failure as the most important fungus isolated from the root canal system. C. albicans has been associated with root ca...

The first part of this study reviewed the characteristics of calcium hydroxide (Ca(OH)2) and summarized the results of in vitro studies related to its antimicrobial effects. The second part of this review covers in vivo studies including human clinical studies and animal studies. The use of Ca(OH)2 as an intracanal medicament represented better histological results in animal studies. However, h...

The purpose of this study was to investigate the effect in vitro on macrophage adhesion of Tifell (formocresoleugenol), used as an intracanal medicament and in therapeutic pulpotomies in primary teeth, Macrophages were obtained from Wistar rats. As a test of macrophage phagocytic function the adherence capacity of macrophages to a plastic surface was determined. Assays were carried out in Eppen...

Root resorption might result in the premature loss of the affected teeth. Most teeth with internal and external root resorption are symptom free and are first clinically recognized through routine radiographs. Calcium hydroxide is used as a temporary intracanal medicament in the management of root resorption followed by mineral trioxide aggregate (MTA) treatment.Lesions appears as a uniform, ro...