An increasing number of studies indicate that the optic nerve head of the eye is sensitive not only to changes in intraocular pressure (IOP), but also to intracranial pressure (ICP). This study examines changes to optic nerve and retinal structure in a rat model in response to a range of IOP and ICP levels using optical coherence tomography. Furthermore, we examine the functional sequelae of th...

This review paper describes innovative methods and technology for non-invasive human brain physiological monitoring based on measuring the acoustic properties of the brain parenchyma. The clinical investigation of new technology shows the similarity between the invasively recorded intracranial pressure (ICP) and non-invasively recorded intracranial blood volume (IBV) pulse waves, slow waves and...

BACKGROUND Although the effects of opioids on intracranial pressure (ICP) have long been a subject of controversy, they are frequently administered to patients with severe head trauma. We present a patient with an uncommon paradoxical response to opioids. CASE REPORT A patient with refractory intracranial hypertension after closed head injury was managed with standard medical therapy with onl...

Intracranial pressure (ICP) and continuous transcranial Doppler ultrasound signals were monitored in 20 head-injured patients and simultaneous synchronous fluctuations of middle cerebral artery (MCA) velocity and B waves of the ICP were observed. Continuous simultaneous monitoring of MCA velocity, ICP, arterial blood pressure, and expired CO2 revealed that both velocity waves and B waves occurr...

Modified electroconvulsive therapy (MECT) is an effective treatment option for schizophrenia, however, concerns on its safety and complications such as increased intracranial pressure (ICP) exists. The purpose of this study was to assess the effects of MECT on ICP in schizophrenic patients and to identify related risk factors. 112 subjects diagnosed with schizophrenia were recruited and allocat...

Head injury is a common form of trauma. For example, in the UK head injury occurs in more than 500 000 persons per annum of which about 10% are diagnosed as severe, 15% moderate and the remainder as minor head injury (Miller et al., 1992; Pickard and Czosnyka, 1993). Head trauma is a significant cause of death and disability, especially in young males (median age < 30) and is associated with ra...

This report examined the intraoperative course of partial pressure of brain tissue oxygen (P(ti)O(2)) and intracranial pressure (ICP) during surgical decompressive craniectomy for medically intractable intracranial hypertension due to diffuse brain swelling in three patients after severe subarachnoid haemorrhage and aneurysm coiling. The mean ICP decreased from 59 mm Hg to 10 mm Hg in a two ste...