PURPOSE To investigate the effects of amifostine on bacterial translocation and overgrowth in colonic flora after acute radiation enteritis in a rat model. METHODS Thirty-two female Wistar albino rats were divided into four groups: Group-1 (n=8): only normal saline was administered intraperitoneally. Group-2 (n=8): first serum saline was administered intraperitoneally and 30 minutes later 20 ...

Trypan red, when injected intraperitoneally into mice, has been found greatly to lower the incidence of the infection of mice inoculated intraperitoneally with the neurotropic MM virus. The protective action of the dye is overcome if the virus is inoculated in too high concentration. The lowered incidence of infection was observed in mice inoculated with virus for as long as 29 days after the l...

Our previous study showed that quercetin enhances the anticancer effect of trichostatin A (TSA) in xenograft mice given quercetin intraperitoneally (10 mg/kg, 3 times/week). Herein, we investigate whether quercetin administered orally exerts such an effect and prevents the cytotoxic side effects of TSA. We found that quercetin given orally (20 and 100 mg/kg, 3 times/week) failed to enhance the ...

The effect of Theranekron® on rat ovaries was evaluated in healthy and ischemia-reperfusion injury models. rats were divided into four groups: group 1: control, 2: (single dose 0.3 mg/kg intraperitoneally), 3: torsion + detorsion, 4: detorsion 0,3 mg/kg, intraperitoneally). homogenized by sonication before the analysis supernatant glucose-6-phosphate dehydrogenase activity, reduced nicotinamide...

the subcutaneous inoculation of 16 white mice and 10 golden hamsters with l.tropica major resulted in the development of leishmanial lesions in all, becoming generalized in some.two of 10 hamsters inoculated intraperitoneally with this parasite developed generalized lesions. on the other hand, the inoculation of l. tropica minor to 128 mice subcutaneously and 170 mice intraperitoneally did not ...