A simple and sensitive spectrophotometric method was developed and validated for the determination of pregabalin in bulk, pharmaceutical formulations and in human urine samples. The method was based on the reaction of drug with the mixture of potassium iodate and potassium iodide. The method was linear in the range of 0.5-3.5 μg/ml. There is no official method for the determination of pregabali...

We report here a derivatization headspace method for the analysis of inorganic iodine in water. Samples from Lake Mead, the Las Vegas Wash, and from Las Vegas tap water were examined. Lake Mead and the Las Vegas Wash contained a mixture of both iodide and iodate. The average concentration of total inorganic iodine (TII) for Lake Mead was approximately 90 nM with an iodide-to-iodate ratio of app...

ERGs and the azide responses were recorded from mice before and periodically up to 6 weeks after retinal pigment epithelium (RPE) damage by iodate injection to follow the recovery of retinal pigment epithelium and retinal function. At 14 days postinjection, there was a partial recovery of the maximal b-wave amplitude and the azide response but no further recovery was found after 14 days. The re...

Iodate is almost immediately reduced to iodide following its intravenous administration to rats or rabbits. Even when it is given in relatively large doses, reduction is complete within 2 to 3 min. Following oral administration also, radioiodate is so rapidly transformed to radioiodide that 2-hour thyroid 13rI uptakes in rats that received radioiodate by stomach tube were not significantly diff...

The iodate reduction by hydrogen peroxide in acidic solutions is part of the Bray-Liebhafsky and Briggs-Rauscher oscillating reactions. At low hydrogen peroxide concentrations, typical of the Bray-Liebhafsky reaction, its rate law is -d[IO(-)(3)]/dt = (k'(R) + k"(R)[H(+)])[IO(-)(3)][H(2)O(2)] with k'(R) = 1.3 × 10(-7)(20°), 7.8 × 10(-7) (39°), 1.4 × 10(-5) M(-1) s(-1) (60°) and k"(R) = 1.5 × 10...

The novel iodate oxychloride, Bi2Te(IO3)O5Cl, has been hydrothermally synthesized and structurally characterized. The compound crystallizes in the polar monoclinic space group Cc with a = 22.037(8) Å, b = 5.256(2) Å, c = 15.142(5) Å, and β = 104.499(7)°. Three types of asymmetric chromophore structural units, that is the electron lone-paired [IO3](-) groups, the second-order Jahn-Teller effect ...

The title salt, C(12)H(14)N(2) (2+)·2IO(3) (-), exhibits two crystallographically independent iodate anions, the I atoms of which are each in a trigonal-pyramidal environment. In the dication, the two pyridine rings adopt an anti conformation with respect to each other; the angle between these two rings is 3.84 (19)°. In the crystal structure, C-H⋯O hydrogen bonds between the cations and anions...

Choline can be covalently grafted on glassy carbon electrodes using cyclic voltammetric method, forming a stable cationic monolayer-modified electrode (Ch/GCE). Keggin-type molybdophosphate anions, alpha-PMo(12)O(40)(3-), then were self-assembled on the Ch/GCE through electrostatic interactions for fabrication of an electrochemical sensor, which is denoted as alpha-PMo(12)/Ch/GCE. This two-laye...

Autocatalytic reaction fronts between two reacting species in the absence of fluid flow, propagate as solitary waves. The coupling between autocatalytic reaction front and forced simple hydrodynamic flows leads to stationary fronts whose velocity and shape depend on the underlying flow field. We address the issue of the chemico-hydrodynamic coupling between forced advection in porous media and ...

Twenty C57 black mice received an injection of 40 mg/kg of sodium iodate through the caudal vein. The electroretinograms (ERGs) were recorded before and after injection. Flash stimuli with the maximum illuminance, 30,000 lux, were given at increasing levels of illuminance in 0.6 log U steps for 13 levels of intensity. The a- and b-wave amplitudes increased linearly with increased stimulus inten...