Positive and negative ions generated by laser-based ionization methods from three gold:thiolate cluster compounds are mass analyzed by time-of-flight mass spectrometry. The three compounds have similar inorganic core masses ( approximately 29 kDa, approximately 145 Au atoms) but different n-alkanethiolate ligands associated with each cluster compound (Au:SR, R = butane, hexane, dodecane). Irrad...

BACKGROUND There is a clinical need for new technologies that would enable rapid disease diagnosis based on diagnostic molecular signatures. Ambient ionization mass spectrometry has revolutionized the means by which molecular information can be obtained from tissue samples in real time and with minimal sample pretreatment. New developments in ambient ionization techniques applied to clinical re...

The U+O chemi-ionization reaction has been investigated by quantum chemical methods. Potential-energy curves have been calculated for several electronic states of UO and UO(+). Comparison with the available spectroscopic and thermodynamic values for these species is reported and a mechanism for the chemi-ionization reaction U+O-->UO(+)+e(-) is proposed. The U+O and Sm+O chemi-ionization reactio...

Using a time-dependent density-functional-theory (TDDFT) method that incorporates the exact exchange, we reproduce the measured ionization suppression for vanadium in 1500-nm lasers of 1.4 to 2.8 × 1013 W/cm2. The calculated ionization yields are 0.07 to 0.5 in 100 fs sin2 pulses. For weaker laser intensities a method with more configurations is needed to properly describe the multiphoton, rath...

In this paper, we present a model for propagation of intense and ultrashort laser pulses ionizing dielectrics. We consider early ionization so that this process is sufficiently weak to avoid requiring a complete description of the ionization process (e.g. the use of kinetic equations which are very expensive from a computational point of view). As the intensity of the field is small, one photon...

Introduction Computed Tomography scans are a very important tool for diagnosis and assessment of response to treatment in the practice of medicine. Ionizing radiation in medical imaging is undoubtedly one of the most powerful diagnostic tools in medicine. Yet, as with all medical interventions, there are potential risks in addition to the clear potential benefits. Materials and Methods Two refe...

Recent progress in femtosecond (fs) tera-watt (TW) laser development has raised a new fundamental question in atomic and molecular physics, i.e., how atoms and molecules react against an intense electromagnetic field. As is well known, an atom exposed to photons of relatively low flux density is ionized only if the photon energy exceeds the ionization potential of the atom. On the other hand, w...

At the ISOLDE on-line isotope separation facility, the resonance ionization laser ion source (RILIS) can be used to ionize reaction products as they effuse from the target. The RILIS process of laser step-wise resonance ionization of atoms in a hot metal cavity provides a highly element selective stage in the preparation of the radioactive ion beam. As a result, the ISOLDE mass separators can p...

We present intensity-resolved above-threshold ionization (ATI) spectra of xenon using an intensity scanning and deconvolution technique. Experimental data were obtained with laser pulses of 58 fs and a central wavelength of 800 nm from a chirped-pulse amplifier. Applying a deconvolution algorithm, we obtained spectra that have higher contrast and are in excellent agreement with characteristic t...