Iron is essential for human life, but toxic if present in excess. To avoid iron overload and maintain iron homeostasis, all cells are able to regulate their iron content through the post-transcriptional control of iron genes operated by the cytosolic iron regulatory proteins that interact with iron responsive elements on iron gene mRNA. At the systemic level, iron homeostasis is regulated by th...

Ferritin iron, hemosiderin iron, total iron stores and transformation rate were determined by serum ferritin kinetics. The transformation rate between ferritin and hemosiderin is motivated by the potential difference between them. The transformer determines transformation rate according to the potential difference in iron mobilization and deposition. The correlations between transformation rate...

background: iron deficiency is the most common single-nutrient deficiency disease in the world and is a major concern for about 15% of the world population.  it has been shown that iron deficiency may affect thyroid hormones.   objective: to determine thyroid hormone status in iron deficient adolescent girls.   methods: a cross-sectional study was carried out in lar province and its’ vicinity i...

to evaluate the effect of foliar application of nano iron chelate and iron chelate fertilizers on morphological traits and essential oil content of holy basil, an experiment was conducted at research farm of department of horticultural, shahid chamran university of ahvaz based on randomized complete blocks design with six treatments and three replications. the treatments were including control,...

in this study, the isothermal reduction of iron oxide pellets, made of iranian chadormalo, gole-gohar, and sangan iron ores, was investigated in the temperature range of 900-1100°c. tabas, pabdana, babnizoo, karmozd, and shahrood domestic coals were used as reductants. parametric studies were performed and the effects of such factors as temperature, average particle size of iron ore and coal fi...

AIMS To compare iron fortified follow-on milk (iron follow-on), iron fortified partially modified cows' milk (iron milk), and iron medicine for the treatment of iron deficiency anaemia (IDA) in hospitalised infants. METHODS In a randomised controlled trial, infants aged 9-23 months with IDA and who were hospitalised with an acute illness received iron follow-on (12 mg/l ferrous iron), iron mi...

aim : to investigate if hepatic iron content influences the response to therapy in patients with chronic hepatitis c or b. background : it seems that the presence of elevated body iron stores and, in particular, elevated hepatic iron levels, is one of the strongest predictors of resistance to interferon treatment for chronic hepatitis c or b. patients and methods : two hundred and one patients ...

introduction: children’s iron deficiency anemia is the most common nutritional problem; it plays an important role in reducing the child’s scientific and practical abilities. this study aims at reviewing the prevalence of iron deficiency anemia in 1 to 6 year old children referring to the city health care centers in jahrom. material and methods: this is a descriptive-analytical and cross-sectio...

Nonheme food ferritin (FTN) iron minerals, nonheme iron complexes, and heme iron contribute to the balance between food iron absorption and body iron homeostasis. Iron absorption depends on membrane transporter proteins DMT1, PCP/HCP1, ferroportin (FPN), TRF2, and matriptase 2. Mutations in DMT1 and matriptase-2 cause iron deficiency; mutations in FPN, HFE, and TRF2 cause iron excess. Intracell...