Mann et al. give important insight into the risk factors and possible pathophysiology not only on ischaemic neonatal stroke (becoming symptomatic during the neonatal period), but also congenital ischaemic stroke (evolving during the first year of life). By analyzing these two entities in parallel they give some answers as to whether we have two different entities here or a similar entity becomi...

Cardiac arrhythmias can be triggered from ischaemic cardiac muscle due to the damage inflicted on individual myocytes. During an ischaemic episode free fatty acids accumulate in the ischaemic tissue. The importance of these fatty acids lies in the apparent ability of some classes of fatty acid to protect against cardiac arrhythmias. As cardiac sudden death is a likely cause of death in patients...

Tissue ischaemia is an important factor in the development of several eye diseases. The commonly accepted idea regarding management of ischaemic effects is that a normal blood flow should be increased. Trimetazidine, an anti-ischaemic agent, can have a positive effect on retinal disorders with an ischaemic component. Trimetazidine seems to have an influence on selected visual parameters (improv...