Multivariate statistical process monitoring techniques are applied to pilot-plant, cell culture data for the purpose of fault detection and diagnosis. Data from 23 batches, 20 normal operating conditions (NOC) and three abnormal, were available. A PCA model was constructed from 19 NOC batches, while the remaining NOC batch was used for model validation. Subsequently, the model was used to succe...

The University of Michigan has developed a xed-wing model aircraft (Solus) with an embedded control system to develop and demonstrate UAV technology. The analytical objective of this project is the development of intelligent ight control and trajectory planning techniques, focusing on automated fault detection and recovery. Our experimental objective is to implement and evaluate these technique...

This work studies potential ways of integration of two techniques for fault detection, isolation, and identification in dynamic systems: Lydia-NG suite of diagnosis algorithms and Consistency-based Diagnosis with Possible Conflicts. By integrating both techniques, LydiaNG will benefit from a more efficient fault detection and isolation task, and Possible Conflicts will benefit from the identifi...

Despite rapid advances in the complementary fields of speciation genetics and molecular phylogenetics, little attention has been devoted to understanding how genetic changes associated with reproductive isolation accumulate across clades of species. We argue that comparative analyses of reproductive isolation QTL (quantitative trait loci) can generate unique insights into the underlying mechani...

Studies of hybrid inviability, sterility and 'speciation genes' in Drosophila have given insight into the genetic changes that result in reproductive isolation. Here, I survey some extraordinary and important advances in Drosophila speciation research. However, 'reproductive isolation' is not the same as 'speciation', and this Drosophila work has resulted in a lopsided view of speciation. In pa...

Determining how a new hybrid lineage can achieve reproductive isolation is a key to understanding the process and mechanisms of homoploid hybrid speciation. Here, we evaluated the degree and nature of reproductive isolation between the ecologically successful hybrid species Pinus densata and its parental species P. tabuliformis and P. yunnanensis. We performed interspecific crosses among the th...

Postzygotic reproductive isolation is characterized by two striking empirical patterns. The first is Haldane's rule--the preferential inviability or sterility of species hybrids of the heterogametic (XY) sex. The second is the so-called large X effect--substitution of one species's X chromosome for another's has a disproportionately large effect on hybrid fitness compared to similar substitutio...

During 2009-10, real time RT-PCR and conventional RT-PCR techniques Used for detecting BTVs RNA in 310 blood samples. For real time and gel based RT-PCR segment-1 and segment-10 selected as conserve genes to search any BTV strains. Using these methods, 58 (%18.7) and 14 (%4.5) positive samples were detected among the clinically suspected sheep. Sensitivity of both molecular techniques evalua...

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The onset of infections by Leishmania parasites mainly caused by amastigote growth inside the macrophages. One of the important properties of lesion-derived amastigote is thought to be the attachment of various host proteins including immunoglobulins on the surface of amastigote. In this study, the presence of immunoglobulins on the surface of lesion-derived amastigotes was detected by Western ...