BACKGROUND Postponement of childbearing since the 1970s has led to an increase in permanent involuntarily childlessness. We will address the magnitude of this trend, the effect of IVF/ICSI and the effect on total fertility rate (TFR an often used demographic measure for the level of fertility) in six EU countries. METHODS Using a fertility micro-simulation model, we estimate the effect of pos...

OBJECTIVE We investigated whether the insemination method (in vitro fertilization [IVF] or intracytoplasmic sperm injection [ICSI]) affected morphokinetic events and abnormal cleavage events in embryonic development. METHODS A total of 1,830 normal fertilized embryos were obtained from 272 IVF and ICSI cycles that underwent ovum retrieval culture using a time-lapse system (Embryoscope) from J...

OBJECTIVE To examine the relationship of early human embryonic development with the level of reactive oxygen species (ROS) in the culture media on the first day (day 1 ROS) after insemination. DESIGN A prospective study. SETTING Patients undergoing assisted reproduction in a teaching hospital. PATIENT(S) Patients undergoing conventional IVF (n = 104; 115 cycles) and intracytoplasmic sperm...

OBJECTIVE To investigate the efficacy of IVF-intracytoplasmic sperm injection (ICSI) in patients who cryobanked semen before cancer treatment. DESIGN Retrospective consecutive study. SETTING University-based IVF unit. PATIENT(S) One hundred eighteen couples undergoing IVF-ICSI using pretreatment frozen sperm. INTERVENTION(S) Treatment follow-up. MAIN OUTCOME MEASURE(S) Semen parameter...

introduction: implantation of transferred embryos in the uterus after ivf_icsi cyclesis an important process that less information about it is available. zona hatching method is a suggested approach for this goal. the aim of this research is about performance of zona hatching by laser. methods: in this study 32 patients that enrolled had ivf/icsi cycles depend on inclusion criteria of study tha...

BACKGROUND Currently, there is no agreement on the optimal urinary derived human chorionic gonadotropin (u-hCG) dose requirement for initiating final oocyte maturation prior to oocyte collection in in vitro fertilization (IVF), but doses that range from 2500- 15000 IU have been used. We intended to determine whether low dose u-hCG was effective for oocyte maturation in IVF/intracytoplasmic sper...

STUDY QUESTION Are we able to develop a model to calculate the chances of pregnancy prior to the start of the first IVF cycle as well as after one or more failed cycles? SUMMARY ANSWER Our prediction model enables the accurate individualized calculation of the probability of an ongoing pregnancy with IVF. WHAT IS KNOWN ALREADY To improve counselling, patient selection and clinical decision-...

Sperm chromatin/DNA damage can be measured by a variety of assays. However, it has been reported that these tests may lose prognostic value in Assisted Reproductive Technology (ART) cycles when assessed in post-prepared samples, possibly due to the normalizing effect promoted by sperm preparation procedures. We have recently implemented a modified version of the Diff-Quik staining assay that al...

We present live births resulting from two separate IVF cycles in a couple in which ICSI was performed with sperm specifically selected for presence of small cytoplasmic droplets. These cycles followed previous cycles using standard sperm selection methods in which very poor embryo development and no pregnancies ensued. The male partner was diagnosed with severe male factor infertility including...

background: In this 10th European IVF-monitoring (EIM) report, the results of assisted reproductive techniques from treatments initiated in Europe during 2006 are presented. Data were mainly collected from existing national registers. methods: From 32 countries, 998 clinics reported 458 759 treatment cycles including: IVF (117 318), ICSI (232 844), frozen embryo replacement (FER, 86 059), egg d...