OBJECTIVES To assess the presence of anti-cyclic citrullinated peptide antibodies in a cohort of patients with juvenile idiopathic arthritis. METHODS Anti-cyclic citrullinated peptide antibodies was tested for with an enzyme linked immunoabsorbent assay (ELISA) in serum samples of patients from the Hospital de Clínicas de Porto Alegre, all less than 18 years old and with previous diagnosis fo...

While the long-term outlook of JRA varies with different forms of the disease, over 1/3 of children in general will have active disease that persists into their adult lives, while the remainder experience a remission by the time they reach adulthood. Moreover, 30-50% of patients experience significant limitations in daily functioning 10 years after the onset of their disease. For these reasons,...

OBJECTIVE To determine the spectrum of clinical presentation, laboratory parameters and drug therapy in patients with Juvenile Rheumatoid Arthritis (JRA). STUDY DESIGN Case series. PLACE AND DURATION OF STUDY The Children's Hospital and The Institute of Child Health, Lahore, from October 2008 to October 2011. METHODOLOGY All patients who fulfilled the American College of Rheumatology crit...

Rheumatoid Arthritis (RA) the musculoskeletal disease of joints, mainly affects elderly people and some cases juvenile rathritis also reported. Until now no particular etiological reason put for initiation and development of the disease. The understanding rheumatoid arthritis has paramount importance, besides no particular mechanisms postulated for etiology have been well documented. In recent ...