Collections of exfoliated cells on Millipore filters, which retain the topographical relationships of the cells collected, previously have been used to examine keratinization and inflammation of adult gingivae. In the present study, samples of epithelial and inflammatory cells were obtained from the anterior maxillary gingivae of threeto five-year-old children using this technique. The oral hyg...

The largest and most vital part of the human body is skin any change in features termed as a lesion. paper considers granular parakeratosis lesion that an epidermal reaction occurring due to disorder keratinization, mainly seen intertriginous areas. manual inspection bit cumbersome which automated system proposed this paper. main goal determine size depth lesions using ensemble algorithm, parti...

Darier's disease (Dyskeratosis follicularis, DD) is a genetic disorder characterized by pathogenetic changes of keratinization with variant forms of cutaneous phenotype. Recently, it has been showed that Darier's disease cause mutations in the ATP2A2 gene, at 12q24.1. The gene encodes sarco-endoplasmic reticulum calcium ATPase type 2 (SERCA2). Mutations in exon 15 are reported to be the most co...

Twenty-four cases of giant condyloma acuminata were found among 100 cases diagnosed as carcinoma of the penis. One of the 24 tumours showed early malignant change. The characteristic histological pattern of giant condyloma consists of broad processes composed of prickle cells associated with little keratinization. The malignant condylomas show, in comparison, a loss of prickle cell preponderanc...

Oral mucosa becomes thinner, smooth and looses stippling aspect with aging. From histological standpoint appears: narrowing and alteration of gingival epithelium, modification of epithelial-connective interface and decreasing of keratinization. However, it cannot be detected significant histological alterations in size, shape or arrangement of epithelial cells that could be endorsed to aging pr...

SYNOPSIS Twenty-four cases of giant condyloma acuminata were found among 100 cases diagnosed as carcinoma of the penis. One of the 24 tumours showed early malignant change. The characteristic histological pattern of giant condyloma consists of broad processes composed of prickle cells associated with little keratinization. The malignant condylomas show, in comparison, a loss of prickle cell pre...

Darier's disease, also known as keratosis follicularis or dyskeratosis follicularis, is a rare disorder of keratinization. It is an autosomal dominant genodermatosis with high penetrance and variable expressivity. Its manifestation appears as hyperkeratotic papules, primarily affecting seborrheic areas on the head, neck, and thorax and less frequently on the oral mucosa. When oral manifestation...

Disseminated superficial porokeratosis (DSP) is a specific disorder of keratinization. Genetic studies show that DSP is an autosomal dominant trait. Clinically, the lesions show a sharply demarcated and hyperkeratotic plaque with central atrophy. The lesions appear mainly in the extremities and generally develop with bilateral symmetry. Unusual cases of DSP accompanied by severe pruritus have b...