BACKGROUND The differential diagnosis of common pigmented skin lesions is important in cosmetic dermatology. The computer aided image analysis would be a potent ancillary diagnostic tool when patients are hesitant to undergo a skin biopsy. OBJECTIVE We investigated the numerical parameters discriminating each pigmented skin lesion from another with statistical significance. METHODS For each...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Chyl-Surdacka K, Borzęcki A, Latifa J, Turska-Kozłowska M, Majchrzycka M. Keratosis follicularis (Darier disease) – clinical characteristics and treatment a review update. Postępy Dermatologii i Alergologii/Advances in Dermatology Allergology. 2023. doi:10.5114/ada.2022.124344. APA Chyl-Surdacka, K., Borzęcki, A.,...

MAPK: mitogen-activated protein kinase MEK: MAPK/ERK kinase INTRODUCTION Several skin lesions resulting from keratinocyte hyperproliferation have been observed in melanoma patients receiving BRAF inhibitor monotherapy. The most common of these lesions are verrucal keratosis, Grover disease, plantar hyperkeratosis, actinic keratosis, cutaneous squamous cell carcinoma, and keratosis pilaris. More...

Actinic keratosis is a common disease in humans, which also affects dogs. Lesions occur in chronically sun exposed areas, such as flank, ventral and lateral abdomen. It has been reported that actinic keratosis is a pre-neoplastic disease which may evolve into squamous cell carcinoma (SCC), which is one of the most frequent malignant neoplasm in dogs. The aim of this research was to investigate ...

OBJECTIVE To provide evidence that lymphomatoid keratosis should be categorized as an epidermotropic subtype of cutaneous lymphoid hyperplasia. DESIGN Clinicopathological, immunohistochemical, and molecular biological studies of epidermotropic and dermal bandlike infiltrates of lymphocytes without necrotic keratinocytes, Civatte bodies, or Max-Joseph spaces and solar lentigo or seborrheic ker...

Background: Untreated actinic keratosis can advance to squamous cell carcinoma, which in turn is associated with a risk of metastasis. Current treatments for actinic keratosis have many shortcomings. This communication describes the efficacy and safety of a topical cream therapy, Curaderm, containing solasodine glycosides (0.005%) for actinic keratosis. Methods: Randomly assigned patients with ...

Clinical Description The patient complained of multiple non-healing sores on his chest and back for 2 years. He had been taking traditional medications for more than 30 years for rheumatism and asthma. He had sought treatment from other clinics previously, and was treated with cryotherapy and excision of some of the chest lesions. These had unfortunately recurred. Clinically, he had numerous er...

The most common health effects from drinking-water containing dissolved arsenic are skin abnormalities and lesions that are typically diagnosed as keratosis and pigment disorder. It was previously reported that the prevalence of cutaneous lesions was about 44% in arsenic-affected villages. However, there has been little research on the relationship between levels of arsenic in drinking-water an...

Keratosis, one of the earliest skin manifestations of arsenicosis, can be treated by either oral or topical formulation of drug. In this study we examined the effectiveness and tolerance of propylene glycol for the treatment of arsenical palmer keratosis. Sixty patients of arsenicosis with palmer keratoses were randomly divided into three groups and different concentrations (15, 30 and 45%) of ...

Squamous cell carcinoma (SCC) of the skin is a tumor with greatly increased incidence among immunosuppressed patients; therefore, an infectious cause of SCC has long been sought. We performed a hospital-based case-control study of Staphylococcus aureus and biopsies of SCC (n = 82), basal cell carcinoma (n = 142), actinic keratosis (n = 57), and seborrhoeic keratosis (n = 72) in comparison with ...