Previously, recipients of a simultaneous pancreas-kidney transplant versus a kidney transplant alone were thought to have higher fracture risk. Using a large US registry, Nikkel et al. observed lower rates of fracture hospitalization among patients with type 1 diabetes after simultaneous pancreas-kidney compared with kidney transplantation alone, particularly among men. It is not known whether ...

Primary hyperoxaluria is a rare autosomal recessive disease due to deficiency of an oxalate-metabolizing liver enzyme, which results in nephrolithiasis and renal failure. Concomitant liver and kidney transplant is recommended as isolated kidney transplant is inevitably complicated by recurrence of the disease. We present a 25-year-old man with end-stage nephrolithiatic renal disease who underwe...

OBJECTIVES Therapeutic monitoring of sirolimus and everolimus is necessary in order to minimize adverse side-effects and to ensure effective immunosuppression. A sirolimus-dosing model using the concentration/dose ratio has been previously proposed for kidney transplant patients, and the aim of our study was the evaluation of this single model for the prediction of trough sirolimus and everolim...

objective: the aim of the present study was to investigate the level of gingival over-growth (go) in patients with kidney transplant. materials and methods: the target group of the study was the patients recently received kidney transplant and cyclosporine-a therapy. by a systematic case selection method, a total of 131 cases were included in the study, of whom 80 (61.6%) patients were male. th...

Background: A wide variety of cutaneous and mucosal lesions occur in renal transplant recipients. Objectives: Evaluation of the skin and mucous membrane lesions in the kidney transplant recipients in Noor and Ali Asghar Hospital in Isfahan. Patients and Methods: This cross-sectional descriptive study was done on 117 patients (82 male, 35 female), who had received kidney transplants and re...

CONTEXT Solitary pancreas transplantation (ie, pancreas alone or pancreas-after-kidney) for diabetes mellitus remains controversial due to procedure-associated morbidity/mortality, toxicity of immunosuppression, expense, and unproven effects on the secondary complications of diabetes. Whether transplantation offers a survival advantage over conventional therapies for diabetes is unknown. OBJE...

BACKGROUND Administrative data are increasingly being used to assess outcomes in kidney transplant recipients. OBJECTIVE To assess the validity of transplant data in healthcare administrative databases compared to the reference standard of information collected directly from transplant centres. DESIGN Retrospective cohort study. SETTING One of three major transplant centres in Ontario (To...

OBJECTIVES Kidney transplant in mouse model is quite useful and valuable for studying transplant immunobiology. However, its technical complexity and high mortality have hindered widespread use. We sought to review and analyze the various techniques of kidney transplant in mice to prevent pitfalls and reduce complications. MATERIALS AND METHODS We searched PubMed using the key words "kidney t...