Background: Invariant natural killer cells (iNKT) are an important immunoregulatory T cell subset. Currently several flow cytometry-based approaches exist for the identifi-cation of iNKT cells, which rely on using the 6B11 monoclonal antibody or a combina-tion of anti-Vα24 and anti-Vβ11 antibodies. Objective: The aim of this study was to compare the ability of two flow cytometry-based methods f...

BACKGROUND The number of type 2 helper CD4+ T cells is increased in the airways of persons with asthma. Whether the majority of these cells are class II major-histocompatibility-complex-restricted cells or are among the recently identified CD1d-restricted invariant natural killer T cells is a matter of controversy. We studied the frequency of invariant natural killer T cells in the airways of s...

Killer lymphocytes provide powerful immune protection from cancer and infection by eliminating dangerous cells. Innate killer cells (principally natural killer cells) and innate-like T cells provide the first response. Antigen-specific immunity by cytotoxic T lymphocytes takes over about a week later and provides life-long immunity. When killer cells recognize a target cell, they mobilize cytot...

background: invariant natural killer cells (inkt) are an important immunoregulatory t cell subset. currently several flow cytometry-based approaches exist for the identifi-cation of inkt cells, which rely on using the 6b11 monoclonal antibody or a combina-tion of anti-vα24 and anti-vβ11 antibodies. objective: the aim of this study was to compare the ability of two flow cytometry-based methods f...

Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system that capable killing virally infected and physiologically stressed cells, like tumor cells. In addition to their ability directly kill cancer NK enhancing both antibody T-cell responses. Moreover, ex vivo activation, expansion, genetic modification can greatly enhance anti-tumor activity equip them overcome resistan...

This report provides a study on the ongoing infection, pathogenesis, and immunity of COVID-19. The will also investigate cytokine storm role both dendritic cells Natural Killer T cells, provide ample references for researchers who need immunological data SARS-CoV-2. review collects from 60 different research articles. Viral antigens are predictable by B or introduced to MHC complexes, leading a...

2010 John Wiley & Sons A/S Immunological Reviews 0105-2896 Granule-mediated cytolysis is undoubtedly the most important effector function of CD8 T cells and natural killer (NK) cells. After a killer cell recognizes its target, the cytotoxic granules, which are specialized secretory lysosomes that store the death-inducing proteins, migrate to the immunological synapse (IS). The cytotoxic granule...