tuberculosis is a major health problem in iran and its laryngeal involvement is not uncommon. laryngeal tuberculosis is so infectious and delay in diagnosis and treatment could result spread of disease and causes divesting complications. we reviewed clinical and para-clinical characteristics of patients with laryngeal tuberculosis in iran. in a cross sectional study, patients with laryngeal tub...

Background Hereditary angioedema (HAE) is a rare disorder characterized by a congenital deficiency of the C1-inhibitor. It is a potentially fatal illness as laryngeal edema may lead to asphyxiation. Treatment of HAE is mainly performed with C1-inhibitor concentrate, icatibant, attenuated androgens, and antifibrinolytic agents. We conducted a systematic review to evaluate the efficacy and safety...

Hair dye poisoning has been emerging as one of the important causes of intentional self harm in the developing world. Hair dyes contain paraphenylene-diamine and a host of other chemicals that can cause rhabdomyolysis, laryngeal edema, severe metabolic acidosis and acute renal failure. Intervention at the right time has been shown to improve the outcome. In this article, we review the various m...

Unfortunately, the treatment of numerous otolaryngological diseases often lacks of evidence base because appropriate studies are missing. Whereas sufficient high-quality trials exist for the specific immunotherapy of allergic rhinitis and in a limited measure also for the angiotensin-converting enzyme inhibitor induced angioedema, the evidence for Menière's disease or for pharmacotherapy of pos...

Background and Objectives Vocal fold (VF) scar is known to be the most common cause of dysphonia after laryngeal microsurgery (LMS). Steroids reduce postoperative formation by inhibiting inflammation collagen deposition. However, clinical evidence whether steroids are helpful in reducing VF LMS still lacking. The purpose this study determine intralesional steroid injection helps voice quality.M...

OBJECTIVE To evaluate the efficacy and safety of prophylactic corticosteroid therapy in preventing postextubation laryngeal edema (PELE) and the need for reintubation in adults. DATA SOURCES Literature was accessed through MEDLINE (1966-January 2008) and the Cochrane Library using the terms laryngeal edema, airway obstruction, postextubation stridor, intubation, glucocorticoids, and corticost...

M e t h o d s Design: Randomized placebo-controlled trial. Allocation: Concealed.* Blinding: Blinded (clinicians and patients).* Follow-up period: Up to 24 hours after extubation. Setting: 7 intensive care units in France. Patients: 761 patients 47 to 74 years of age (mean age 66 y, 64% men) who were mechanically ventilated for > 36 hours (median duration 6 d) and were to be extubated in the in...

obstructed, accounted for the timing; small caliber and high transmural pressures, for the character. I advocate the term “chirping rales” for this singular finding. (One must caution against the possibility ofconfusing the term “chirping rales” with “chirpes,” the latter designating a well-known and regrettably common disorder of amorous songbirds.) More euphonious than “squawk, the onomatopoe...

To the Editor: Ezri et al.1 described serum electrolyte changes following ingestion of cathartics prior to bowel resection surgery. The authors dosed 90 mL of Fleet® Phospho-soda® to their subjects. This is twice the recommended dose of 30–45 mL according to the current professional Fleet® Phospho-soda® labelling.2 Fleet® Phospho-soda® should be used only at the recommended dosage and only in p...