Laryngopharyngeal or gastroesophageal reflux is associated with laryngeal airway hyperreactivity (LAH), but neither the cause-effect relationship nor the underlying mechanism has been elucidated. Here we established a rat model with enhanced laryngeal reflex reactivity induced by laryngeal acid-pepsin insult and investigated the neural and hydroxyl radical (*OH) mechanisms involved. The larynge...

Introduction:Dystonia is a disorder of movement caused by various etiologies. Laryngeal dystonia is caused by the spasm of laryngeal muscles. It is a disorder caused by vocal fold movement in which excessive adduction or abduction of the vocal folds occurs during speech. The pathophysiology of this type of dystonia is not fully known. Some researchers have suggested that basal ganglia structure...

OBJECTIVE To examine the effect of recurrent laryngeal nerve section on myonuclear addition and myofiber remodeling in adult rabbit laryngeal muscles. STUDY DESIGN AND SETTING Unilateral section of the recurrent laryngeal nerve was performed on adult rabbits. Rabbits were labeled with bromodeoxyuridine, euthanized, and the laryngeal muscles were examined for bromodeoxyuridine (brdU) and neona...

BACKGROUND Supraglottic airway devices are increasingly important in clinical anesthesia and prehospital emergency medicine, but there are only few data to assess the risk for aspiration. We designed this study to compare the seal of seven supraglottic airway devices in a cadaver model of elevated esophageal pressure. METHODS The classic laryngeal mask airway, laryngeal mask airway ProSeal, i...

OBJECTIVE To investigate the correlation between extracellular matrix protein-1 (ECM1) and the growth, metastasis and angiogenesis of laryngeal carcinoma. MATERIALS AND METHODS Forty-five samples with laryngeal benign and malignant tumors confirmed by pathology in Laiwu City People's Hospital from March 2006 to March 2011 were collected, in which there were 29 cases with laryngeal carcinoma a...

introduction: injury to cranial nerves ix, x, and xii is a known complication of laryngoscopy and intubation. here we present a patient with concurrent hypoglossal and recurrent laryngeal nerve paralysis after rhinoplasty. case report: the patient was a 27-year-old woman who was candidate for rhinoplastic surgery. the next morning after the operation, the patient complained of dysphonia and a s...

non‑recurrent laryngeal nerve (nrln) is a rare anomaly which is reported in 0.3%‑0.8% of people on the right side and in 0.004% (extremely rare) on the left side. damage to this nerve during the surgical procedure may lead to severe iatrogenic morbidity and should therefore be prevented from being damaged. the best way to avoid this damage to the nerve is to identify the nerve with a systematic...

introduction: cigarette smoking and alcohol consumption have a well-known effect on the development of upper aerodigestive tract carcinomas, but such a role for opium is questionable. this study was designed to assess the correlation between opium inhalation and cancer of the larynx and upper esophagus. materials and methods: fifty eight patients with laryngeal cancer, ninety eight patients wit...

background: potassium permanganate (pp) is a highly corrosive and deadly agent with a reported lethal dose of 10 g in adults. in this report, successful treatment of a patient poisoned with three times the lethal dose of pp is presented, and effective and early approach to such emergency toxicologic condition is discussed. case presentation:a 24-year-old woman presented to emergency room of our...

conclusions endoscopic keel placement should be done with heavy suture through cricothyroid and thyrohyoid membranes. surgeons should suture the keel to the anterior laryngeal wall with specially designed lichtenberger’s needle-carriers to prevent complications such as keel aspiration, adhesion formation and imposing a second trip under general anesthetics, which put the patient at increased ri...