Background: Leptin and its receptors have been found in the human gastric mucosa.  Its secretion by gastric mucosa has generated interest in its probable role in the gastrointestinal tract and pathophysiology of diseases. Objective: To determine any possible correlation between serum leptin level and pathological findings in patients with duodenal ulcer (DU). Methods: In a cross-sectional study...

Objectives Periodontal disease is an inflammatory condition of the tooth-supporting structures. Leptin is a hormone produced by the human body under different circumstances such as infection. It affects the production of cytokines, phagocytosis and the inflammation process. This study aimed to compare the salivary level of leptin in chronic periodontitis (CP) patients and healthy controls. Met...

osteoporosis is a systemic skeletal disease and there is a close relationship between the sympathetic nervous system (sns) and bone metabolism. leptin has been shown to regulate bone formation and bone resorption via the sns. however, the effect of sns on leptin signaling has not been clearly understood. in the present study, we studied the effect of propranolol on ovariectomy-induced osteoporo...

Recently, extensive efforts have been made to understand the rate of energy expenditure and the weight gain associated with atypical antipsychotic treatment, including identification of markers of obesity risk. In recent years, leptin, an adipocyte hormone, has gained significant interest in psychiatric disorders. S100B has been considered as a surrogate marker for astrocyte-specific damage in ...

Background: It seems that in vaginal delivery, serum leptin level increases as a cortisol-dependent factor due to the stress of the embryo. Studies have shown that if the level of serum leptin is low, the risk of chronic metabolic diseases, cardiovascular diseases, hypertension, and obesity in the mother and the baby will increase. Objectives: The aim of this study was to determine the relatio...

leptin is secreted mainly by fat, which is involved in energy metabolism and reproduction. leptin and itsreceptor (ob-r) have been detected in human spermatozoa and testis, thus it can be concluded leptin involves in male physiology. the goal of this study was determination of the presence of leptin receptor mrna in the ram testis, epididymis and spermatozoa by reverse transcription polymerase ...

background: leptin has been implicated in the differentiation and proliferation of hematopoietic cells. leukemia inhibitory factor (lif) may play an important role, along with interleukin-6 (il-6) and granulocyte colony stimulating factor (g- csf), in the regulation of early hematopoietic stem cells. the aim of the study was to evaluate serum level of leptin, lif, and il-6 in myeloid leukemia p...