background: edifenphos, a kind of organophosphate toxins, is used as agricultural fungicides in rice fields. this study was aimed to investigate the effect of temperature on lethal concentration of exposure to edifenphos on rutilus frisii kutum (caspian kutum). methods: the experiment was carried out in static condition and based on instructions of oecd within 10 d under controlled water physic...

Present study consists the effect of sub lethal levels of heavy metals zinc and mercury on the activities of enzymes like HMG Co A reductase, lactate dehydrogenase and serine hydrolyase in Oreochromis mossambicus. Activities of the enzymes varied depending on the duration of exposure to the toxicants. Feasibility of measuring the enzyme activities in monitoring sub lethal metal poisoning is als...

Background: Barbiturate poisoning is rare but potentially fatal. Case Report: We reported a case of barbiturate in 28-year-old woman who recovered from lethal pentobarbital deliberate self-poisoning. The initial blood concentration was 61 mg/L, corresponding to dose. Despite the ingestion high dose pentobarbital, electroencephalogram revealed an unattended pattern compatible with possible nonco...

One of the most extreme examples of gene dosage sensitivity is the Triplo-lethal locus (Tpl) on the third chromosome of Drosophila melanogaster, which is lethal when present in either one or three copies. Increased dosage of an unlinked locus, Isis, suppresses the triplo-lethal phenotype of Tpl, but not the haplo-lethal phenotype. We have mapped Isis to the X chromosome region 7E3-8A5, and show...

The capacity of heterozygous yellow-lethal (Aya) and brown (aa) male mice to induce the Bruce effect was investigated. The proportion of SJL/J females showing a failure of implantation when exposed to males of either genotype was 80 %, whereas only 20 % of the control females not so exposed showed pregnancy failure. One-half of the females whose pregnancy had been blocked as a result of exposur...

Lethal and sterility mutations were accumulated in a cage population which was initiated with lethal- and sterility-free second chromosomes of D. melanogaster. It took about 2,000 days for the frequencies of these genes to reach equilibrium levels, i.e., 18% lethal and 9% male-sterile chromosomes. Two other cage populations which were initiated with random chromosomes sampled from natural popul...