SIR,-I wish to refer to the excellent article by Drs. H. G. Miller, J. B. Stanton, and J. L. Gibbons on acute disseminated encephalomyelitis (Journal, March 23, p. 668). Unfortunately, however, it perpetuates an error which has crept into the literature concerning the reports of cases in which the condition of acute haemorrhagic leuco-encephalitis has complicated an infectious exanthem. In 1945...

genic leucocytes from donor blood are responsible for serious untoward effects in some transfused patients such as alloimmunization, febrile reactions, platelet refractoriness, transfusion associated acute lung injury, immunosuppression as well as transmission or reactivation of viruses such as CMV, HTLV or EBV. Leucocytes are also known to accelerate the rate of storage lesion. The optimal met...

The polyphenolic components in the cambial tissues of several eucalypt species are mainly C6 compounds in the form of ellagitannins; shikimic acid is also present in appreciable quantities (Hillis & Carle, 1958, 1962; W. E. Hillis, unpublished work). When the cambial tissues of eucalypts are injured in the growing season, a faint-brown liquid commonly exudes and dries to a brown or brown-red, b...

water plays a vital and essential role in our ecosystem. this natural resource is becoming scarce, making its availability a major social and economic concern. use of a large variety of synthetic dyes in textile industries has raised an hazardous environmental alert. about 17 - 20% of freshwater pollution is caused by textile effluents. these effluents are recalcitrant to biodegradation and cau...

A 2-year-old girl with 5,10-methylenetetrahydrofolate reductase deficiency developed subacute combined degeneration of the cord and a leuco-encephalopathy which was confirmed at necropsy. Total folate concentrations in serum, red cells and CSF were markedly reduced whereas vitamin B12 concentrations were normal. In addition the patient had Parkinsonism and reduced concentrations of homovanillic...

This guide to the neurological disorder cerebral autosomal dominant arteriopathy with subcortical infarcts and leuco encephalopathy (CADASIL) is specifically targeted at psychiatrists. The aims are to enhance awareness, provide educational clinical information and offer practical guidance on management of the disorder. An overview of diagnostic algorithms and recent research is also provided. M...