Circulating antibody to endotoxin core glycolipid and total serum immunoglobulin concentrations were measured in 86 children with cancer (54 with acute lymphoblastic leukaemia, four with acute myeloid leukaemia, and 28 with various solid tumours). Measurements were made before treatment in the group with acute lymphoblastic leukaemia as well as when patients were both on and off chemotherapy. I...

introduction: this paper used generalized gamma (gg) distribution to find the predictive factors of overall survival (os) after haematopoietic stem cell transplant (hsct) in acute myeloid  leukemia patients. methods: discrimination among the exponential, weibull, gg, log-logistic, and lognormal distributions was done using maximum likelihood and akaike information criteria. results: the 5-year ...

BACKGROUND The current situation in the treatment of chronic myeloid leukaemia (CML) presents a new challenge for attempts to measure the therapeutic results, as the CML patients can experience multiple leukaemia-free periods during the course of their treatment. Traditional measures of treatment efficacy such as leukaemia-free survival and cumulative incidence are unable to cope with multiple ...

A diagnosis of chronic granulocytic leukaemia was made in a man who had been haemodialysed for three years. The association between leukaemia and chronic renal failure is rare.

Daunorubicin has been used in the treatment of six cases of acute lymphoblastic and thirteen cases of acute myeloblastic and mono-myeloblastic leukaemia. Complete remissions were obtained in eight patients, three with acute lymphoblastic leukaemia and five with acute myeloblastic leukaemia. Marrow aplasia makes the drug difficult to administer, but no patients died from this cause, in this seri...

The case is presented of a 5 year old boy who attended after an inversion injury. He had persistent pain despite treatment and was subsequently diagnosed with acute myelogenous leukaemia. It is well recognised that acute leukaemia commonly presents as non-traumatic limb pain. This case highlights the need to consider acute leukaemia in the differential diagnosis of any persisting bone or joint ...

The K562 Chronic Myeloid Leukaemia Cell Line undergoes Apoptosis in Response to 4-chloro-5-iodo-7H-pyrrolo[2.3-d]pyrimidine

with the present specifications for clasification, 95% of chronic myelogeneous leukaemia (cml) cases have the t(9;22), which brings the abl oncogene to the bcr region and results in a hybrid gene bcr/abl. there may be involvement of other chromosomes in 2-10%, and secondry or additional chromosome abberations may present in 60-80% during the progression of the disease. in the majority of the re...

s 2008;112:753. 21. Mills KI, Gilkes AF, Hernandez JM et al. A molecular classification of leukaemia reveals MDS as a disease continuum with non-leukaemia and AML sub groups. Haematologica 2007;92:165. 22. Kohlmann A, Kipps TJ, Rassenti LZ et al. An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: the Microarray Innov...

Focal granulomatous giant cell reticulosis was observed in lymph nodes from treated cases of chronic lymphatic and chronic myeloid leukaemia. On the basis of clinical behaviour and histological appearance, it seems plausible that in the terminal phase of leukaemia non-neoplastic reactive reticulosis developed very similar in appearance to lymphogranulomatosis. The possible relationship between ...