background and objective: vascular endothelial growth factor (vegf) is a cytokine which is overexpressed in many malignant cancers including leukemia. vegf plays an important role in tumor invasion and metastasis. determination of the pattern of vegf expression in human leukemic cell lines could be useful not only in screening of new antileukemic agents but also to study the mechanism of their ...

acute myeloblastic leukemia is one of the important malignancies in children. for better managing the prognosis of this disease, there should be enough information about common features of this malignancy. the aim of this study was to evaluate these common features in children with acute myeloblastic leukemia. a total of 104 eligible children less than 15-year-old have been referred from 2007-2...

Leukemia is a malignant disease of Hematopoietic tissue which characterized by the replacement marrow element from normal bone abnormal/neoplastic blood cells. The main treatment for leukemia chemotherapy. Chemotherapy has side effects both physically and psychosocially. first source stress that occurs in parents caused children who are hospitalized, then second can be surrounding environment, ...

We report bilateral proptosis as the unusual initial presentation of juvenile myelomonocytic leukemia in a Ugandan child. Juvenile was diagnosed with complete blood count and bone marrow aspiration biopsy. This is first description orbital involvement occurring setting leukemia, despite leukemic infiltration relatively common middle East, Asia, Africa. In general, simultaneous neoplastic both o...

The production of blood cells is affected by leukemia, a type bone marrow cancer or cancer. Deoxyribonucleic acid (DNA) related to immature cells, particularly white and damaged in various ways this disease. When radiologist involved diagnosing acute leukemia the diagnosis time consuming needs provide better accuracy. For purpose, many types research have been conducted for automatic leukemia. ...

Background Among all malignances, leukemia has the greatest effects on patients 'psychological aspects. Anxiety is common problem in leukemia patients (especially in children). Since no study has addressed the effect of Slow-stroke back massage (SSBM) on anxiety in the pediatrics with chronic leukemia, this investigation aimed to controlling anxiety through a non-drug method (such as SSBM) in c...

Background: Several studies have examined the presence of DNA methylation of CpG islands in leukemia. Methylation of SOX17 and RUNX3 genes may play a role in leukemogenesis through silencing tumor suppressor genes. We investigated the methylation status of SOX17 and RUNX3 genes in patients with acute leukemia.    Methods: In this case-control study, peripheral blood samples from 100 AML and 10...

Background The most common malignancy of children is Leukemia, accounting approximately one third of cancer diagnosis. Available data demonstrate improvement in survival of pediatric leukemia, so evaluation of side effects of treatment is very important. This study investigates hyperglycemia and diabetes mellitus prevalence in pediatric patients with acute leukemia. Materials and Methods T...