Structural and quantitative polymorphisms have been described in human CR1. In the former, the S allotype is larger than the F allotype by 40-50 kD, the size of a long homologous repeat (LHR). In the latter, homozygotes for a 7.4-kb Hind III fragment express fourfold more CR1 per erythrocyte than do homozygotes for the allelic 6.9-kb restriction fragment. The basis for these genomic polymorphis...

We previously reported the existence of a contact-inducible, enhanced invasion phenotype in the obligate human pathogen Neisseria gonorrhoeae. Our present studies showed that the ability of glutaraldehyde-fixed eucaryotic cells to convert gonococci (GC) to this invasive phenotype (Inv+) is limited to cells derived from reproductive tissues. We present evidence that GC recognize the lutropin rec...

OBJECTIVES To compare outcomes in pregnancies with a prenatal detection of congenital diaphragmatic hernia (CDH) with children diagnosed after birth, treated at the same institution, and to determine the ability to predict prognosis through measurements of the observed to expected lung-to-head ratio (O/E LHR). METHODS This is a retrospective review of all children with CDH treated at our inst...

The luteinizing hormone receptor (LHR) is a G protein-coupled receptor involved in regulation of ovarian and testicular functions. Here we show that the receptor is present also in specific areas of the peripheral and central nervous system and may thus have a broader functional role than has been anticipated. Full-length LHR mRNA and two receptor protein species of M(r) 90,000 and 73,000, repr...

Stimulation of gonadal cells by lutropins such as human chorionic gonadotropin (hCG) is often transient and followed by down-regulation and/or desensitization of lutropin receptors (LHR). Here we describe desensitization/resensitization of LHR in Y-1 adrenal cell lines (termed Y-1L) expressing a rat cDNA lacking most 5' and 3' LHR untranslated regions under the control of a metallothionein prom...

Heat treatment is a widely used process to reduce bacterial loads in the food industry or to decontaminate surfaces, e.g., in hospital settings. However, there are situations where lower temperatures must be employed, for instance in case of food production such as raw milk cheese or for decontamination of medical devices such as thermo-labile flexible endoscopes. A recently identified locus of...

The existence of Jalan Pendidikan connects Mataram District with Ampenan District. comfort and safety road users really need to be considered in accordance the initial planning for construction city road. increasing number vehicles that pass every day influence weather have caused some parts damaged. This research was conducted find out damage occurred activities needed done improve condition d...

experiments were conducted to evaluate the performance of a low heat rejection (lhr) diesel engine. performance parameters and emission levels were determined at various magnitudes of brake mean effective pressure. combustion characteristics of the engine were measured with tdc (top dead centre) encoder, pressure transducer, console and special pressure-crank angle software package at peak load...

We present column CO2 measurements taken by the passive miniaturized laser heterodyne radiometer (Mini-LHR) at 1611.51 nm at the Mauna Loa Observatory in Hawaii. The Mini-LHR was operated autonomously, during the month of May 2013 at this site, working in tandem with an AERONET sun photometer that measures aerosol optical depth at 15-min intervals during daylight hours. Laser heterodyne radiome...

ZFP36L2 protein destabilizes AU-rich element-containing transcripts and has been implicated in female fertility. In the C57BL/6NTac mouse, a mutation in Zfp36l2 that results in the decreased expression of a form of ZFP36L2 in which the 29 N-terminal amino acid residues have been deleted, ΔN-ZFP36L2, leads to fertilized eggs that arrest at the two-cell stage. Interestingly, homozygous ΔN-Zfp36l2...