This research is focused on investigating the biochemical mechanisms involved in neurovascular inflammation, cerebral hypoxia and altered cerebral metabolism, with particular focus on their role in the pathogenesis of cerebral malaria (CM) and acute bacterial meningitis (ABM). The pathogenesis of these diseases remains poorly understood, hindering the development of improved therapies. Previous...

This paper illustrates systematic development of a convenient analytical method for the determination of chromium and cadmium in tannery wastewater using laser-induced breakdown spectroscopy (LIBS). A new approach was developed by which liquid was converted into solid phase sample surface using absorption paper for subsequent LIBS analysis. The optimized values of LIBS parameters were 146.7 mJ ...

This article presents the results obtained by measuring characteristic x-ray production cross sections arising from interaction of accelerated protons with target atoms (PIXE). The PIXE data were measured at excitation K-, L-, and M-shells in mass range Mg to Bi 1 MeV protons. We use approach based on calculation through Rutherford backscattering section, which can be calculated formula high ac...

Laser induced breakdown spectroscopy (LIBS) can be used to determine solid, liquid, colloidal, and biological samples. It is a promising technique for analysis and characterization of the composition of a broad variety of objects. This review describes in brief the basic principles and technological aspects of LIBS, and the most recent progress of the various applications of this technique in b...

Ultrasmall SnO2 nanocrystals as anode materials for lithium-ion batteries (LIBs) have been synthesized by bubbling an oxidizing gas into hot surfactant solutions containing Sn-oleate complexes. Annealing of the particles in N2 carbonifies the densely packed surface capping ligands resulting in carbon encapsulated SnO2 nanoparticles (SnO2/C). Carbon encapsulation can effectively buffer the volum...

Laser-induced breakdown spectroscopy (LIBS) using double-pulse irradiation with Nd:YAG and CO(2) lasers was applied to the analysis of a polystyrene film on a silicon substrate. An enhanced emission signal, compared to single-pulse LIBS using a Nd:YAG laser, was observed from atomic carbon, as well as enhanced molecular emission from C(2) and CN. This double-pulse technique was further applied ...

BACKGROUND Inflammation and myocardial necrosis play important roles in ischemia/reperfusion injury after coronary artery occlusion and recanalization. The detection of inflammatory activity and the extent of myocardial necrosis itself are of great clinical and prognostic interest. We developed a dual, noninvasive imaging approach using molecular magnetic resonance imaging in an in vivo mouse m...

By laser induced breakdown spectroscopy (LIBS) analysis of epidermal lesion and dermis tissue pellets of hairless mouse, it is shown that Ca intensity in the epidermal lesion is higher than that in dermis, whereas Na and K intensities have an opposite tendency. It is demonstrated that epidermal lesion and normal dermis can be differentiated with high selectivity either by univariate or multivar...

The potential of laser-induced breakdown spectroscopy (LIBS) to discriminate biological and chemical threat simulant residues prepared on multiple substrates and in the presence of interferents has been explored. The simulant samples tested include Bacillus atrophaeus spores, Escherichia coli, MS-2 bacteriophage, α-hemolysin from Staphylococcus aureus, 2-chloroethyl ethyl sulfide, and dimethyl ...

BACKGROUND Transplant vasculopathy is the main limiting factor of the long-term success of heart transplantation. We sought to establish the role of platelets in the development and progression of transplant vasculopathy. METHODS AND RESULTS Platelet analysis and intracoronary ultrasound examination were performed in 78 heart transplant recipients. Quantitative intracoronary ultrasound was us...