Chronic sleep curtailment in humans has been related to impairment of glucose metabolism. To better understand the underlying mechanisms, the purpose of the present study was to investigate the effect of acute sleep deprivation on glucose tolerance in rats. A group of rats was challenged by 4-h sleep deprivation in the early rest period, leading to prolonged (16 h) wakefulness. Another group of...

In cats reared in the dark from birth until 4 months of age, the dorsal lateral geniculate nucleus contained few normal Y cells in either the binocular or monocular segments. Although most of the neurons appeared to be normal X cells unaffected by light deprivation, many cells with abnormal receptive field and response charcteristics were encountered. These effects were permanent, since 1 to 2 ...

OBJECTIVES This study examines the effects of total light deprivation on the developing lateral geniculate nucleus, the primary integration centre for visual information METHODS Sprague-Dawley rats were reared for one month in a dark room from 7th postnatal day before eye opening. A group of rats was taken back into normal condition for 15 days, and then perfused. Coronal sections of LGN were...

Monocular deprivation results in anatomical changes in the visual cortex in favor of the non-deprived eye. Although the retina forms part of the visual pathway, there is scarcity of data on the effect of monocular deprivation on its structure. The objective of this study was to describe the effects of monocular deprivation on the retinal ganglion cell dendritic features. The study design was qu...

We measured ocular alignment in the horizontal direction for 17 monkeys reared under deprivation paradigms that involved monocular defocus, monocular occlusion and optically corrected aphakia coupled with continuous or partial occlusion of the fellow eye. Alignment was measured at 3 and 7 months with a photographic corneal light reflex method. Results showed that a majority of the monkeys in ea...

In light of widespread agreement that poverty and social exclusion should be understood as multidimensional phenomenon, in this paper we explore the practical implications of such an understanding in relation to widely employed indicators of such phenomena in Ireland. One persistent critique of the current national measures of poverty and social exclusion comes from those who feel that the find...

Background: The increase of stress following the technological improvements appears to be an important factor that causes organs disorders like genital system. Therefore the present study was conducted to investigate the effects of chronic multiple sequential stress on rat epididim. Materials and Methods: 18 Wistar rats were divided randomly into two equal groups. In animals under stress, the m...

Background: The increase of stress following the technological improvements appears to be an important factor that causes organs disorders like genital system. Therefore the present study was conducted to investigate the effects of chronic multiple sequential stress on rat prostate. Materials and Methods: 18 Wistar rats were divided randomly into two equal groups. In animals under stress, the m...

we investigated the effects of 25 mg-porphyrin-fullerene nanoparticles, ( 25 mgpmc16) smart ferroporphyrin nanoparticles, on pc12 cells exposed to oxygen-glucose deprivation/reperfusion. in order to explore its effect on cells under oxygen-glucose deprivation conditions, the cultures were pretreated with 25 mgpmc16 24 hours prior to oxygen-glucose deprivation/reperfusion. to initiate the oxygen...

Dormal G, Collignon O. Functional selectivity in sensory-deprived cortices. J Neurophysiol 105: 2627–2630, 2011. First published March 23, 2011; doi:10.1152/jn.00109.2011.—In a recent study, Lomber, Meredith, and Kral (2010) investigated crossmodal reorganization in congenitally deaf cats. They demonstrated that specific regions of the auditory cortex are responsible for distinct supranormal vi...