Tie1 is a receptor tyrosine kinase expressed in endothelial cells, where it modulates Angiopoietin/Tie2 signaling. Previous studies have shown that mouse mutants exhibit severe cardiovascular defects; however, much remains to be learned about the role of Tie1, especially during cardiac development. To further understand function, we generated zebrafish tie1 mutant line. Homozygous embryos displ...

Background: In several conditions we have face cranial bone defects. Reconstruction of these defects remains one of the most challenging problems encountered by craniofacial surgeons. Objective: To evaluate bone repair in cranial bone defects by use of an implant made of octacalcium phosphate in combination with bone matrix gelatin (OCP/BMG). Methods: We used 40, 5–6-week-old male Sprague-Dawle...

background: in several conditions we have face cranial bone defects. reconstruction of these defects remains one of the most challenging problems encountered by craniofacial surgeons.   objective: to evaluate bone repair in cranial bone defects by use of an implant made of octacalcium phosphate in combination with bone matrix gelatin (ocp/bmg).   methods: we used 40, 5–6-week-old male sprague-d...

introduction : use of adipose-derived stem cells (adscs) is a suggested hypothesis to enhance the regeneration of bone defects. this technique is of particular interest since adscs are more easily accessible via a non-invasive harvesting technique compared to bone marrow stem cells (bmscs). this study sought to assess the efficacy of adsc implantation for regeneration of localized mandibular bo...

Background: Palate is a complex structure separating oro- and nasopharynx. However, reconstruction of the defects of palate is much simpler because of the versatile mucoperiosteal flaps. Here, we present our experience of palatal mucoperiosteal flap used in different situations. Methods: Fifteen patients of palatal as well as buccal mucosa defects were reconstructed using either free or pedicl...

Defect prediction can be a powerful tool to guide the use of quality assurance resources. However, while lots research covered methods for defect as well methodological aspects research, actual cost saving potential is still unclear. Within this article, we close gap and formulate model software prediction. We derive mathematically provable boundary conditions that must fulfilled by models such...

The origin of defects present in a device is not always clear. Hence, in electronic device simulation, the influence of defects with more than two different charge states multivalent defects is often modeled as a set of defects with only two possible charge states Shockley–Read–Hall SRH -like defects which follow the SRH statistics. This paper investigates under which circumstances this procedu...

Abstract Composed of microscopic layers that stack along one direction while maintaining fluid-like positional disorder within layers, smectics are excellent systems for exploring topology, defects and geometric memory in complex confining geometries. However, the coexistence crystalline-like characteristics makes lamellar liquid crystals notoriously difficult to model—especially presence large...